| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1020203 | B | Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS method | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA1020204 | B | Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometer | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 3. | ALA1020205 | F | Cytotoxicity against mouse P388/S cells after 72 hrs by colorimetric tetrazolium-formazan method | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA1020206 | F | Cytotoxicity against human MKN45 cells after 72 hrs | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA1020207 | F | Cytotoxicity against human DLD1 cells after 72 hrs | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 6. | ALA1020208 | F | Cytotoxicity against human HeLa cells after 72 hrs | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 7. | ALA1020209 | B | Inhibition of PKC | 4 | assay format | Scientific Literature | |||
| 8. | ALA1020210 | B | Inhibition of EGFR | 4 | single protein format | Scientific Literature | |||
| 9. | ALA1020212 | F | Antitumor activity in human MKN45 cells xenografted iv dosed nude mouse assessed as tumor growth inhibition administered 5 times per week for 2 weeks at tumor growth of >= 0.2 cm2 | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA1020213 | T | Toxicity in human MKN45 cells xenografted iv dosed nude mouse | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA1021037 | T | Safety margin, ratio of LD10 for nude mouse to GID75 for human MKN45 cells | 4 | cell-based format | Scientific Literature | |||
| 12. | ALA1021038 | F | Antitumor activity in human MX1 cells xenografted iv dosed nude mouse assessed as tumor growth inhibition administered twice per week for 2 weeks | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA1021040 | T | Toxicity in human MX1 cells xenografted iv dosed nude mouse | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA1021041 | T | Safety margin, ratio of LD10 for nude mouse to GID75 for human MX1 cells | 4 | cell-based format | Scientific Literature |
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