# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1020203 | Binding | Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS method | Mus musculus | 30 | ALA1138509 | cell-based format | Scientific Literature | |
2. | ALA1020204 | Binding | Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometer | Homo sapiens | 30 | ALA1138509 | single protein format | Scientific Literature | |
3. | ALA1020205 | Functional | Cytotoxicity against mouse P388/S cells after 72 hrs by colorimetric tetrazolium-formazan method | Mus musculus | 30 | ALA1138509 | cell-based format | Scientific Literature | |
4. | ALA1020206 | Functional | Cytotoxicity against human MKN45 cells after 72 hrs | Homo sapiens | 30 | ALA1138509 | cell-based format | Scientific Literature | |
5. | ALA1020207 | Functional | Cytotoxicity against human DLD1 cells after 72 hrs | Homo sapiens | 30 | ALA1138509 | cell-based format | Scientific Literature | |
6. | ALA1020208 | Functional | Cytotoxicity against human HeLa cells after 72 hrs | Homo sapiens | 29 | ALA1138509 | cell-based format | Scientific Literature |