| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA966955 | Binding | Inhibition of N-terminal flag-tagged Aurora A expressed in Escherichia coli BL21-DE3 by ELISA | 48 | ALA1138512 | assay format | Scientific Literature | ||
| 2. | ALA969659 | Binding | Inhibition of N-terminal flag-tagged Aurora B expressed in Escherichia coli BL21-DE3 by ELISA | 6 | ALA1138512 | assay format | Scientific Literature | ||
| 3. | ALA969660 | Binding | Inhibition of CDK2/cyclin A | 6 | ALA1138512 | single protein format | Scientific Literature | ||
| 4. | ALA969661 | Functional | Antiproliferative activity against human HCT116 cells after 4 days by celltiter assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 5. | ALA969662 | Functional | Antiproliferative activity against human HT-29 cells after 4 days by celltiter assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 6. | ALA973502 | Binding | Inhibition of Aurora A in human HCT116 cells assessed as complete failure of centrosome seperation by immunofluorescence assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 7. | ALA973503 | Binding | Inhibition of Aurora A in human HCT116 cells assessed as complete loss of phospho-Aurora A staining in centrosomes by immunofluorescence assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 8. | ALA973504 | Binding | Inhibition of Aurora B in human HCT116 cells assessed as complete loss of phospho-histamine H3 staining by immunofluorescence assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 9. | ALA973505 | Binding | Inhibition of Aurora B in human HT29 cells assessed as complete loss of phospho-histamine H3 staining by immunofluorescence assay | Homo sapiens | 6 | ALA1138512 | cell-based format | Scientific Literature | |
| 10. | ALA973508 | Binding | Inhibition of GST-fused TPX2/Aurora A complex expressed in Escherichia coli BL21-DE3 relative to Aurora A kinase domain | 5 | ALA1138512 | assay format | Scientific Literature | ||
| 11. | ALA973509 | Binding | Selectivity ratio of IC50 for Aurora B to IC50 for Aurora A | 6 | ALA1138512 | assay format | Scientific Literature | ||
| 12. | ALA973510 | Binding | Inhibition of GST-fused full length wild type Aurora A expressed in Escherichia coli BL21-DE3 relative to Aurora A kinase domain | 5 | ALA1138512 | assay format | Scientific Literature |
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