# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1960329 | F | Antifungal activity against Trichophyton mentagrophytes IBT 2724 after 7 days by micro broth dilution method | Trichophyton mentagrophytes | 28 | organism-based format | Scientific Literature | ||
2. | ALA1960332 | F | Antifungal activity against Trichophyton rubrum IBT 29284 after 7 days by micro broth dilution method | Trichophyton rubrum | 19 | organism-based format | Scientific Literature | ||
3. | ALA1960333 | F | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability after 48 hrs by MTT assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
4. | ALA1021922 | F | Inhibition of centrosomal clustering in human SCC114 cells expressing GFPalpha-tubulin assessed as mitotic cells with multipolar spindles by fluorescence microscopy | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
5. | ALA3407029 | F | Antiproliferative activity against exponentially growing adherent human HCC1937 cells assessed as inhibition of cell proliferation after 72 hrs by luminescence detection based ATPlite assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
6. | ALA3407030 | F | Antiproliferative activity against exponentially growing adherent human HCC1937 cells assessed as inhibition of cell proliferation at 10 uM after 72 hrs by luminescence detection based ATPlite assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
7. | ALA3407167 | F | Antiproliferative activity against exponentially growing adherent human SCC114 cells assessed as inhibition of cell proliferation after 72 hrs by luminescence detection based ATPlite assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
8. | ALA3795965 | P | Thermodynamic solubility in PBS buffer at 1 mg after 12 hrs by HPLC analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA3795966 | A | Half life in mouse liver microsomes by HPLC analysis in presence of NADPH | Mus musculus | 6 | tissue-based format | Scientific Literature | ||
10. | ALA3795967 | A | Half life in rat liver microsomes by HPLC analysis in presence of NADPH | Rattus norvegicus | 6 | tissue-based format | Scientific Literature | ||
11. | ALA3795969 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by celltiter Glo assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
12. | ALA3795970 | F | Cytotoxicity against human U2OS cells assessed as reduction in cell viability after 72 hrs by celltiter Glo assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
13. | ALA4014696 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
14. | ALA4014697 | F | Antiproliferative activity against human U2OS cells after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
15. | ALA4014698 | A | Stability in rat plasma assessed as compound remaining at 1 uM after 120 mins by LC-MS/MS method | Rattus norvegicus | 10 | cell-free format | Scientific Literature | ||
16. | ALA4014699 | A | Stability in mouse plasma assessed as compound remaining at 1 uM after 120 mins by LC-MS/MS method | Mus musculus | 10 | cell-free format | Scientific Literature | ||
17. | ALA4014700 | U | Stability in simulated gastric fluid at pH 1.2 assessed as compound remaining at 1 uM after 120 mins by LC-MS/MS method | 10 | assay format | Scientific Literature | |||
18. | ALA4014701 | A | Intrinsic clearance in CD1 mouse liver microsomes assessed per mg protein at 3 uM preincubated for 45 mins followed by NADPH addition by LC-MS/MS method | Mus musculus | 10 | assay format | Scientific Literature | ||
19. | ALA4014702 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes assessed per mg protein at 3 uM preincubated for 45 mins followed by NADPH addition by LC-MS/MS method | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
20. | ALA4014703 | A | Fraction unbound in rat plasma at 5 uM by LC-MS/MS method | Rattus norvegicus | 10 | cell-free format | Scientific Literature |