# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA974422 | B | Induction of mouse cysteine-less MDR3 ATPase activity relative to basal activity | Mus musculus | 26 | single protein format | Scientific Literature | ||
2. | ALA974425 | B | Induction of mouse cysteine-less MDR3 ATPase activity by apparent Michaelis-Menten constant | Mus musculus | 26 | single protein format | Scientific Literature | ||
3. | ALA974427 | B | Induction of human histidine10-tagged MDR1 ATPase activity expressed in BHK cells relative to basal activity | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
4. | ALA974428 | B | Induction of human histidine10-tagged MDR1 ATPase activity expressed in BHK cells by apparent Michaelis-Menten constant | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
5. | ALA974431 | A | Permeability from apical to basolateral side of MDCK2 cells over expressing MDR1 at 5 uM after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
6. | ALA974432 | A | Permeability from apical to basolateral side of MDCK2 cells over expressing MDR1 at 5 uM in presence LSN335984 pretreated for 30 mins measured after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
7. | ALA974433 | A | Permeability from basolateral to apical side of MDCK2 cells over expressing MDR1 at 5 uM after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
8. | ALA974434 | A | Permeability from basolateral to apical side of MDCK2 cells over expressing MDR1 at 5 uM in presence LSN335984 pretreated for 30 mins measured after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
9. | ALA1021061 | A | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MDCK2 cells over expressing MDR1 at 5 uM after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
10. | ALA1021062 | A | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MDCK2 cells over expressing MDR1 at 5 uM after 1 hr in presence LSN335984 pretreated for 30 mins measured after 1 hr | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
11. | ALA1021063 | A | Normalized ratio of efflux ratio in MDR1 expressing MDCK2 cells to efflux ratio in MDR1 expressing MDCK2 cells in presence of LSN335984 | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
12. | ALA1021064 | A | Permeability from apical to basolateral side of MDCK2 cell monolayer over expressing MDR1 assessed as drug concentration associated with cell at 5 uM after 1 hr of drug washout by methanol | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
13. | ALA1021065 | A | Permeability from apical to basolateral side of MDCK2 cell monolayer over expressing MDR1 assessed as drug concentration associated with cell at 5 uM after 1 hr of drug washout by methanol in presence of LSN335984 | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
14. | ALA1021066 | A | Ratio of permeability from apical to basolateral side after 1 hr of drug washout by methanol to apical to basolateral side in MDCK2 cell monolayer over expressing MDR1 at 5 uM after 1 hr of drug washout by methanol in presence LSN335984 | Canis lupus familiaris | 14 | cell-based format | Scientific Literature | ||
15. | ALA1021067 | P | Octanol-water partition coefficient, log P of the compound | 11 | small-molecule physicochemical format | Scientific Literature |