| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA966957 | B | Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter | Homo sapiens | 80 | cell-based format | Scientific Literature | ||
| 2. | ALA966958 | F | Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assay | Homo sapiens | 67 | cell-based format | Scientific Literature | ||
| 3. | ALA966960 | F | Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assay relative to PACAP38 | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
| 4. | ALA3738744 | B | Displacement of Ac-[125I]-PACAP27 from recombinant human PAC1 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3738745 | B | Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA3738746 | B | Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC2 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA3738747 | F | Neuroprotective activity against MPP+-induced toxicity in human SH-SY5Y cells assessed as increase in cell viability at 100 nM preincubated for 4 hrs followed by incubation with MPP+ for 20 hrs measured after 24 hrs by MTS assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3738748 | B | Activation of PAC1 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3738749 | F | Activation of VPAC1 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3738750 | F | Activation of VPAC2 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | cell-based format | Scientific Literature |
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