# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA715566 | B | Negative logarithm of relative affinity (pRA) towards melatonin receptor (relative to N-acetyl-5-methoxytryptamine (aMT)) | Coturnix | 132 | ALA1131632 | protein format | Scientific Literature | |
2. | ALA712439 | B | Binding affinity towards melatonin receptor was determined using 2-[125I]iodomelatonin as radioligand in chick brain membranes | Gallus gallus | 27 | ALA1127919 | cell membrane format | Scientific Literature | |
3. | ALA874168 | B | inhibitory concentration against Melatonin receptor | Coturnix | 17 | ALA1131632 | protein format | Scientific Literature | |
4. | ALA714927 | B | Binding affinity for Melatonin receptor using 2-[125I]iodomelatonin as radioligand | Coturnix | 17 | ALA1131632 | protein format | Scientific Literature | |
5. | ALA713109 | B | Inhibition of 2-[125I]iodomelatonin binding to Melatonin receptor 3 (MT3) of Syrian hamster brain membrane | 12 | ALA1135933 | assay format | Scientific Literature | ||
6. | ALA713259 | B | Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cells | Homo sapiens | 12 | ALA1135933 | cell-based format | Scientific Literature | |
7. | ALA714100 | F | Intrinsic activity evaluated on [35S]GTP-gamma-S, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1A | 3 | ALA1136758 | cell-based format | Scientific Literature | ||
8. | ALA715950 | B | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1A, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]iodomelatonin | 4 | ALA1136758 | cell-based format | Scientific Literature | ||
9. | ALA715954 | B | Binding Affinity (pKi) towards human Melatonin receptor type 1A | 3 | ALA1136758 | single protein format | Scientific Literature | ||
10. | ALA710593 | F | Intrinsic activity evaluated on [35S]GTP-gamma-S, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1B | 3 | ALA1136758 | cell-based format | Scientific Literature | ||
11. | ALA713142 | B | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1B, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]iodomelatonin | 4 | ALA1136758 | cell-based format | Scientific Literature | ||
12. | ALA858415 | B | Binding Affinity (pKi) towards human Melatonin receptor type 1B | 4 | ALA1136758 | single protein format | Scientific Literature | ||
13. | ALA710823 | B | Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1B expressed in HEK293 cells | Homo sapiens | 12 | ALA1135933 | cell-based format | Scientific Literature | |
14. | ALA841235 | B | Selectivity ratio of binding affinity at MT1 receptor relative to MT3 receptor | Homo sapiens | 12 | ALA1135933 | assay format | Scientific Literature | |
15. | ALA881807 | B | Selectivity ratio of binding affinity at MT2 receptor relative to MT3 receptor | Homo sapiens | 12 | ALA1135933 | assay format | Scientific Literature | |
16. | ALA839211 | B | Ratio of IC50 to that IC50 aMT (aMT=melatonin N-acetyl-5-methoxytryptamine) | Coturnix | 17 | ALA1131632 | single protein format | Scientific Literature | |
17. | ALA1016924 | B | Displacement of [125I]iodomelatonin from MT3/QR2 melatonin binding site expressed in CHO cells | 39 | ALA1154476 | cell-based format | Scientific Literature | ||
18. | ALA3231300 | F | Antiovulatory activity in Sprague-Dawley rat assessed as blockage of luteinizing hormone surge by measuring reduction in ovulation at 8 mg/kg, po by microscopic analysis | Rattus norvegicus | 8 | ALA3228039 | organism-based format | Scientific Literature | |
19. | ALA4056998 | B | Inhibition of QR2 (unknown origin) using MTT and NMeH as substrates | Homo sapiens | 11 | ALA4052743 | single protein format | Scientific Literature | |
20. | ALA4057001 | B | Inhibition of QR2 (unknown origin) using MTT and NMeH as substrates relative to control | Homo sapiens | 11 | ALA4052743 | single protein format | Scientific Literature |