# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA647696 | F | In vitro percent protective effect against Amyloid Beta(A beta)-induced neurotoxicity in B103 cells | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
2. | ALA2089751 | B | Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate assessed as p-nitrophenol release after 30 mins | Homo sapiens | 8 | single protein format | Scientific Literature | ||
3. | ALA983166 | F | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess method | Mus musculus | 5 | cell-based format | Scientific Literature | ||
4. | ALA983167 | A | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells by Griess method | Mus musculus | 5 | cell-based format | Scientific Literature | ||
5. | ALA977683 | B | Inhibition of rat liver microsomal ACAT | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
6. | ALA1775651 | F | Antiproliferative activity against rat HSC-T6 cells at 100 uM after 48 hrs by MTT assay | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
7. | ALA4004086 | F | Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classic pathway preincubated for 10 mins with guinea pig serum followed by erythrocyte addition measured after 30 mins by spectrophotometer | Ovis aries | 33 | cell-based format | Scientific Literature | ||
8. | ALA4004087 | F | Anticomplement activity in New Zealand White rabbit erythrocytes assessed as concentration required for 50% hemolytic inhibition by alternative pathway preincubated for 10 mins with normal human serum followed by erythrocyte addition measured after 30 mins by spectrophotometer | Oryctolagus cuniculus | 33 | cell-based format | Scientific Literature | ||
9. | ALA4477438 | B | Inhibition of GST-tagged human PTP1B expressed in Escherichia coli using pNPP substrate assessed as reduction in p-nitrophenol release | Homo sapiens | 10 | assay format | Scientific Literature | ||
10. | ALA4611852 | F | Cytoprotective activity against LPS-induced NRK-52E cells assessed as reduction in cell death measured every 5 min for 72 hrs by xCELLigence based RTCA analysis | Rattus norvegicus | 31 | cell-based format | Scientific Literature | ||
11. | ALA5263914 | F | Hepatoprotective activity in CCl4-induced toxicity in liver injured mouse assessed as increase in inhibition of liver damage at 50 uM relative to control | Mus musculus | 2 | organism-based format | Scientific Literature |