| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA762824 | B | Inhibitory activity against phosphodiesterase 5 (PDE5) obtained from human corpus cavernosum tissue | 28 | single protein format | Scientific Literature | |||
| 2. | ALA759930 | B | Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expression | 25 | cell-based format | Scientific Literature | |||
| 3. | ALA2024710 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum GHA infected in human erythrocytes after 72 hrs using malstat staining by spectrophotometry | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
| 4. | ALA2024711 | A | Cytotoxicity against human MRC5 SV2 cells after 72 hrs using resazurin by fluorimetry | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA2024712 | A | Selectivity ratio of CC50 for human MRC5 SV2 cells to IC50 for chloroquine-sensitive Plasmodium falciparum GHA strain | 28 | cell-based format | Scientific Literature | |||
| 6. | ALA2024713 | B | Inhibition of bovine PDE5 after 24 hrs by time-resolved fluorescence resonance energy transfer assay | Bos taurus | 15 | single protein format | Scientific Literature | ||
| 7. | ALA2024715 | U | Selectivity index, ratio of IC50 for chloroquine-sensitive Plasmodium falciparum GHA to IC50 for bovine PDE5 | 5 | assay format | Scientific Literature | |||
| 8. | ALA2024717 | B | Inhibition of human recombinant PDE1B expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2024718 | B | Inhibition of human recombinant PDE2A expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2024719 | B | Inhibition of human recombinant PDE3A expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2024720 | B | Inhibition of human recombinant PDE4A1A expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2024721 | B | Inhibition of human PDE5 using [3H]5GMP at 10 uM after 60 mins by scintillation counting | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA2024722 | B | Inhibition of bovine PDE6 using [3H]5GMP at 10 uM after 60 mins by scintillation counting | Bos taurus | 1 | assay format | Scientific Literature | ||
| 14. | ALA2024723 | B | Inhibition of human recombinant PDE7A expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2024724 | B | Inhibition of human recombinant PDE8A1 expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2024725 | B | Inhibition of human recombinant PDE10A1 expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2024726 | B | Inhibition of human recombinant PDE11A4 expressed in Sf9 cells at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!