| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA649491 | B | Inhibition of [125I]AII binding to guinea pig adrenal membrane | Cavia porcellus | 13 | assay format | Scientific Literature | ||
| 2. | ALA650301 | B | Inhibition of [125I]angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1 | Cavia porcellus | 27 | assay format | Scientific Literature | ||
| 3. | ALA650302 | B | Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane preparation | Cavia porcellus | 8 | cell membrane format | Scientific Literature | ||
| 4. | ALA650303 | F | In vitro antagonistic potency against Angiotensin II receptor, type 1 in guinea pig adrenal membrane | Cavia porcellus | 3 | cell membrane format | Scientific Literature | ||
| 5. | ALA770464 | F | Inhibition of angiotensin II-induced contractions in rabbit aorta in vitro. | Oryctolagus cuniculus | 21 | tissue-based format | Scientific Literature | ||
| 6. | ALA782143 | F | Tested in vivo for inhibition of pressor response induced by infusion of AII in conscious normotensive rats, when given intravenously | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 7. | ALA780390 | F | Compound was evaluated by intravenous administration to conscious rats for inhibition of pressor response induced by infusion of AII(n=3-10) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA781109 | F | Effective dose following intravenous administration to conscious rats for inhibition of AII-induced pressor response | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 9. | ALA1669992 | F | Antagonist activity at angiotensin AT1 receptor in rabbit aorta | Oryctolagus cuniculus | 18 | tissue-based format | Scientific Literature | ||
| 10. | ALA1670685 | B | Binding affinity to angiotensin AT1 receptor in guinea pig adrenal cortex membranes | Cavia porcellus | 5 | cell membrane format | Scientific Literature | ||
| 11. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | small-molecule physicochemical format | AstraZeneca Deposited Data | |||
| 12. | ALA3301364 | P | ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the method described in J. Assoc. Lab. Autom. 2011, 16, 276-284. Experimental range 0.10 to 1500 uM | 1,763 | small-molecule physicochemical format | AstraZeneca Deposited Data |
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