# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA961866 | F | Growth inhibition of mouse B16 2F2 cells after 3 days | Mus musculus | 21 | ALA1148134 | cell-based format | Scientific Literature | |
2. | ALA961867 | F | Induction of melanogenesis in mouse B16 2F2 cells assessed as intracellular melanin content after 3 days | Mus musculus | 17 | ALA1148134 | cell-based format | Scientific Literature | |
3. | ALA4417324 | B | Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange method | Homo sapiens | 30 | ALA4414666 | cell-based format | Scientific Literature | |
4. | ALA4417325 | B | Inhibition of human recombinant 5-LOX expressed in insect cells assessed residual activity using arachidonic acid at 42 uM as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange method relative to control | Homo sapiens | 30 | ALA4414666 | cell-based format | Scientific Literature | |
5. | ALA4417326 | B | Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange assay | Homo sapiens | 30 | ALA4414666 | assay format | Scientific Literature | |
6. | ALA4417327 | B | Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 20 mins in dark by ferric ion oxidation-xylenol orange assay relative to control | Homo sapiens | 30 | ALA4414666 | assay format | Scientific Literature | |
7. | ALA4417328 | B | Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | Ovis aries | 30 | ALA4414666 | single protein format | Scientific Literature | |
8. | ALA4417329 | B | Inhibition of ovine recombinant COX1 assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | Ovis aries | 30 | ALA4414666 | single protein format | Scientific Literature | |
9. | ALA4417330 | B | Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis | Homo sapiens | 30 | ALA4414666 | cell-based format | Scientific Literature | |
10. | ALA4417331 | B | Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as residual activity at 42 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis relative to control | Homo sapiens | 30 | ALA4414666 | cell-based format | Scientific Literature |