# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA961078 | Functional | Antiproliferative activity against human Col2 cells after 3 days by sulforhodamine B assay | Homo sapiens | 10 | ALA1148122 | cell-based format | Scientific Literature | |
2. | ALA961079 | Functional | Induction of cell differentiation of human HL60 cells at 4 ug/mL after 4 days by non-specific esterase determination | Homo sapiens | 10 | ALA1148122 | cell-based format | Scientific Literature | |
3. | ALA961080 | Functional | Inhibition of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a BALB/c mouse mammary gland culture at 10 ug/mL treated for 10 days before DMBA-challenge measured after 14 days | Mus musculus | 9 | ALA1148122 | tissue-based format | Scientific Literature | |
4. | ALA2169390 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as SHP promoter transactivation by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
5. | ALA2169391 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells at 10 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
6. | ALA2169393 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as SHP promoter transactivation at 100 nM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
7. | ALA2169394 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as SHP promoter transactivation at 10 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
8. | ALA2169395 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as SHP promoter transactivation at 1 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 1 | ALA2163343 | cell-based format | Scientific Literature | |
9. | ALA2169396 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as ABCA1 promoter transactivation at 100 nM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 3 | ALA2163343 | cell-based format | Scientific Literature | |
10. | ALA2169397 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as ABCA1 promoter transactivation by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
11. | ALA2169398 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as ABCA1 promoter transactivation at 10 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
12. | ALA2169399 | Functional | Agonist activity at human PPARgamma expressed in human HEK293 cells assessed as ABCA1 promoter transactivation at 1 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
13. | ALA2169400 | Binding | Inhibition of fluormone binding to human PPARgamma LBD after 2 hrs by competitive fluorescence polarization assay | Homo sapiens | 4 | ALA2163343 | single protein format | Scientific Literature | |
14. | ALA2169401 | Binding | Transactivation of PPARalpha expressed in human HepG2 cells assessed as Sult2a1 expression at 10 uM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 3 | ALA2163343 | cell-based format | Scientific Literature | |
15. | ALA2169590 | Binding | Transactivation of PPARalpha expressed in human HepG2 cells assessed as Sult2a1 expression at 100 nM by luciferase reporter gene assay relative to vehicle-treated control | Homo sapiens | 2 | ALA2163343 | cell-based format | Scientific Literature | |
16. | ALA3075308 | Binding | Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 100 nM after 48 hr by luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA3046494 | cell-based format | Scientific Literature | |
17. | ALA3075309 | Binding | Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 1 uM after 48 hr by luciferase reporter gene assay relative to control | Homo sapiens | 3 | ALA3046494 | cell-based format | Scientific Literature | |
18. | ALA3075310 | Binding | Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 10 uM after 48 hr by luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA3046494 | cell-based format | Scientific Literature | |
19. | ALA3075311 | Binding | Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of GAL4 gene expression at 100 nM after 48 hr by luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA3046494 | cell-based format | Scientific Literature | |
20. | ALA3075020 | Binding | Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of GAL4 gene expression at 1 uM after 48 hr by luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA3046494 | cell-based format | Scientific Literature |