# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA947712 | B | Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia coli | Rattus norvegicus | 34 | assay format | Scientific Literature | ||
2. | ALA941398 | F | Cytotoxicity against human PRMI7951 cells by tetrazolium salt-based colorimetric assay | Homo sapiens | 58 | cell-based format | Scientific Literature | ||
3. | ALA941399 | F | Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
4. | ALA941400 | F | Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
5. | ALA941401 | F | Cytotoxicity against human HCT8 cells by tetrazolium salt-based colorimetric assay | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
6. | ALA941402 | F | Cytotoxicity against human TE671 cells by tetrazolium salt-based colorimetric assay | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
7. | ALA4371843 | F | Neuroprotective activity against glutamate-induced neuronal cell death in mouse HT22 cells at 10 to 20 uM by microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4371844 | F | Neuroprotective activity against glutamate-induced neuronal cell death in mouse HT22 cells assessed as increase in cell viability at 20 to 50 uM after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA4371845 | F | Antioxidant activity assessed as DPPH free radical scavenging activity up to 15 uM incubated for 30 mins | 1 | assay format | Scientific Literature | |||
10. | ALA4371846 | F | Antioxidant activity in mouse HT22 cells assessed as reduction in glutamate-induced increase in intracellular reactive oxygen species level at 10 to 20 uM after 8 hrs by H2DCFDA staining based fluorescence microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA4371847 | F | Neuroprotective activity against glutamate-induced neuronal cell death in mouse HT22 cells assessed as reduction in intracellular calcium level at 10 to 20 uM after 8 hrs by fluorescence microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4371848 | B | Inhibition of glutamate-induced ERK1/2 phosphorylation in mouse HT22 cells at 10 to 20 after 8 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
13. | ALA4371849 | B | Inhibition of glutamate-induced JNK phosphorylation in mouse HT22 cells at 10 to 20 after 8 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
14. | ALA4371850 | B | Inhibition of glutamate-induced p38 MAPK phosphorylation in mouse HT22 cells at 10 to 20 after 8 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4371851 | F | Inhibition of glutamate-induced apoptosis in mouse HT22 cells assessed as apoptotic cells at 10 uM after 12 hrs by AlexaFluor 488-Annexin V/propidium iodide staining-based assay (Rvb = 54%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
16. | ALA4371852 | F | Inhibition of glutamate-induced apoptosis in mouse HT22 cells assessed as apoptotic cells at 20 uM after 12 hrs by AlexaFluor 488-Annexin V/propidium iodide staining-based assay (Rvb = 54%) | Mus musculus | 1 | cell-based format | Scientific Literature |