| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2040304 | B | Inhibition of Dengue virus NS5 polymerase assessed as inhibition of radiolabeled guanosine incorporation into homopolymeric cytosine RNA template by liquid scintillation counting | Dengue virus | 12 | assay format | Scientific Literature | ||
| 2. | ALA1941510 | B | Inhibition of Dengue virus 2 NS5 polymerase-mediated RNA synthesis expressed in Escherichia coli Rosetta pLac1 cells assessed as [3H]GTP incorporation after 5 mins by scintillation counting | dengue virus type 2 | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA1941511 | B | Inhibition of Bovine diarrhea virus NS5 polymerase-mediated RNA synthesis expressed in Escherichia coli Rosetta pLac1 cells assessed as [3H]GTP incorporation after 5 mins by scintillation counting | Bovine viral diarrhea virus 1 | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA983730 | B | Inhibition of HCV NS5B polymerase assessed as chain termination of RNA synthesis | Hepatitis C virus | 4 | assay format | Scientific Literature | ||
| 5. | ALA4137220 | B | Inhibition of Influenza virus A/X-31 RNA dependent RNA polymerase using ApG primer [adenyl (3'-5') guanosine] and [8-3H]GTP after 1 hr by filter-based assay | Influenza A virus (A/X-31(H3N2)) | 7 | assay format | Scientific Literature | ||
| 6. | ALA4338389 | A | Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 7. | ALA4338390 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Mus musculus | 41 | assay format | Scientific Literature | ||
| 8. | ALA4338391 | A | Substrate activity at recombinant full-length chicken CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Gallus gallus | 41 | assay format | Scientific Literature | ||
| 9. | ALA4338392 | A | Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 10. | ALA4338393 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Mus musculus | 41 | assay format | Scientific Literature | ||
| 11. | ALA4338394 | A | Substrate activity at recombinant full-length chicken CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Gallus gallus | 41 | assay format | Scientific Literature |
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