# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615542 | F | Insulin-sensitizing activity; triglyceride accumulation from insulin regulated differentiation of 3T3-L1 cells at 1 uM expressed as percent activity of pioglitazone | Mus musculus | 17 | ALA1132799 | cell-based format | Scientific Literature | |
2. | ALA615543 | F | Compound was tested for insulin-sensitizing activity by measuring triglyceride accumulation from insulin regulated differentiation of 3T3-L1 cells at 10 uM expressed as percent activity of pioglitazone | Mus musculus | 7 | ALA1132799 | cell-based format | Scientific Literature | |
3. | ALA690739 | F | Insulin-releasing activity in HIT-T15 cells in the presence of 16.7 mM glucose at 10 uM expressed as percent activity of nateglinide | Cricetulus griseus | 17 | ALA1132799 | cell-based format | Scientific Literature | |
4. | ALA736130 | F | Hypoglycemic activity causing more than a 20% blood glucose decrease in fasting mice | Mus musculus | 15 | ALA1124511 | organism-based format | Scientific Literature | |
5. | ALA978088 | F | Increase in insulin releasing activity in Syrian golden hamster HIT-T15 cells at 1 uM after 1 hr relative to control | Mesocricetus auratus | 21 | ALA1156707 | cell-based format | Scientific Literature | |
6. | ALA978089 | F | Increase in insulin releasing activity in Syrian golden hamster HIT-T15 cells at 10 uM after 1 hr relative to control | Mesocricetus auratus | 21 | ALA1156707 | cell-based format | Scientific Literature | |
7. | ALA978090 | F | Increase in insulin releasing activity in Syrian golden hamster HIT-T15 cells at 100 uM after 1 hr relative to control | Mesocricetus auratus | 21 | ALA1156707 | cell-based format | Scientific Literature | |
8. | ALA978091 | F | Increase in insulin releasing activity in Syrian golden hamster HIT-T15 cells after 1 hr | Mesocricetus auratus | 10 | ALA1156707 | cell-based format | Scientific Literature | |
9. | ALA1035433 | A | Total body clearance in human | Homo sapiens | 390 | ALA1151930 | organism-based format | Scientific Literature | |
10. | ALA1035434 | A | Renal clearance in human | Homo sapiens | 390 | ALA1151930 | organism-based format | Scientific Literature | |
11. | ALA1043580 | A | Fraction unbound in human plasma | Homo sapiens | 276 | ALA1156824 | cell-free format | Scientific Literature | |
12. | ALA1043581 | A | Total clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
13. | ALA1043582 | A | Hepatic clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
14. | ALA1043583 | A | Renal clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
15. | ALA1043584 | A | Oral bioavailability in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
16. | ALA1043585 | A | Fraction absorbed in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
17. | ALA1043586 | A | Fraction escaping gut-wall elimination in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
18. | ALA1043587 | A | Fraction escaping hepatic elimination in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
19. | ALA1043588 | A | Volume of distribution at steady state in human | Homo sapiens | 300 | ALA1156824 | organism-based format | Scientific Literature | |
20. | ALA1614670 | A | Volume of distribution at steady state in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature |