# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1016585 | B | Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
2. | ALA1016588 | B | Inhibition of glutamate-induced depolarization in human EAAT2 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA1016589 | B | Inhibition of glutamate-induced depolarization in human EAAT3 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA1016590 | B | Inhibition of [3H]D-Asp uptake at EAAT1 in HEK293 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
5. | ALA1016591 | B | Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
6. | ALA1013069 | B | Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
7. | ALA1013084 | B | Displacement of [3H]AMPA from AMPA receptor in rat synaptosomes | Rattus norvegicus | 9 | subcellular format | Scientific Literature | ||
8. | ALA1013086 | B | Displacement of [3H]CGP 39653 from NMDA receptor in rat synaptosomes | Rattus norvegicus | 9 | subcellular format | Scientific Literature | ||
9. | ALA981982 | B | Displacement of [3H]KA from KA receptor in rat synaptosomes | Rattus norvegicus | 9 | subcellular format | Scientific Literature | ||
10. | ALA3789011 | F | Agonist activity at mGlu2 receptor (unknown origin) assessed as IP1 accumulation preincubated with 3 uM LY341495 for 20 mins followed by addition of 1 mM of compound by IP-One functional assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
11. | ALA3789012 | F | Agonist activity at rat mGlu1 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assay | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
12. | ALA3789013 | F | Agonist activity at rat mGlu5 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assay | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
13. | ALA3789014 | B | Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assay | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
14. | ALA3789015 | B | Agonist activity at rat mGlu3 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assay | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
15. | ALA3789016 | F | Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as inhibition of forskolin stimulated cAMP production | Rattus norvegicus | 13 | cell-based format | Scientific Literature | ||
16. | ALA3789017 | F | Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP production | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA3789018 | B | Selectivity index, ratio of EC50 for rat mGlu3 receptor expressed in HEK293 cells to EC50 for rat mGlu2 receptor expressed in HEK293 cells | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA3789019 | F | Agonist activity at rat mGlu1 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
19. | ALA3789020 | F | Agonist activity at rat mGlu5 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
20. | ALA3789021 | F | Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature |