| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1032351 | Binding | Inhibition of HCV 1b histidine tagged NS5B-delta55 polymerase-mediated RNA synthesis expressed in Escherichia coli BL21 cells assessed as decrease in accumulation of pppGC product | Hepatitis C virus subtype 1b | 8 | ALA1140133 | organism-based format | Scientific Literature | |
| 2. | ALA1032352 | Functional | Antiviral activity against HCV 1b in human Huh-5-2 cells assessed as inhibition of viral replication after 72 hrs by luciferase assay | Hepacivirus hominis | 4 | ALA1140133 | organism-based format | Scientific Literature | |
| 3. | ALA1032353 | ADME | Cytotoxicity against human Huh-5-2 cells after 3 days by MTS assay | Homo sapiens | 4 | ALA1140133 | cell-based format | Scientific Literature | |
| 4. | ALA1246840 | ADME | Cytotoxicity against human HuH6 cells after 3 days by MTS/PMS method | Homo sapiens | 10 | ALA1240527 | cell-based format | Scientific Literature | |
| 5. | ALA1246841 | Functional | Antiviral activity against HCV1b infected in human HuH6 cells assessed as inhibition of viral RNA replication after 3 days by RT-PCR analysis | Hepacivirus hominis | 10 | ALA1240527 | organism-based format | Scientific Literature | |
| 6. | ALA1246842 | Binding | Inhibition of HCV recombinant His6x-tagged NS5B Cdelta55 polymerase-mediated RNA synthesis expressed in Escherichia coli BL21(DE3) assessed as reduction of pppGpC accumulation after 15 mins | Hepatitis C virus | 24 | ALA1240527 | assay format | Scientific Literature |
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