# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA986283 | Functional | Antiinflammatory activity against collagen-induced arthritis in po dosed Lewis rat model assessed as inhibition of paw swelling | Rattus norvegicus | 1 | ALA1140163 | organism-based format | Scientific Literature | |
2. | ALA986284 | Functional | Antiinflammatory activity against collagen-induced arthritis Lewis rat model assessed as area under the paw swelling curve at 0.04 mg/kg, po relative to control | Rattus norvegicus | 1 | ALA1140163 | organism-based format | Scientific Literature | |
3. | ALA986285 | Binding | Inhibition of Lyn | 1 | ALA1140163 | single protein format | Scientific Literature | ||
4. | ALA1024853 | Binding | Inhibition of p38alpha | 11 | ALA1140163 | single protein format | Scientific Literature | ||
5. | ALA1024854 | Binding | Inhibition of KDR | 10 | ALA1140163 | single protein format | Scientific Literature | ||
6. | ALA1024855 | Binding | Inhibition of Lck | 10 | ALA1140163 | single protein format | Scientific Literature | ||
7. | ALA1024856 | Binding | Inhibition of cKit | 11 | ALA1140163 | single protein format | Scientific Literature | ||
8. | ALA1025669 | Binding | Inhibition of JNK1 | 10 | ALA1140163 | single protein format | Scientific Literature | ||
9. | ALA1025670 | Binding | Inhibition of JNK2 | 10 | ALA1140163 | single protein format | Scientific Literature | ||
10. | ALA1025671 | Binding | Inhibition of JNK3 | 10 | ALA1140163 | single protein format | Scientific Literature | ||
11. | ALA1025672 | Binding | Inhibition of PDGFR | 1 | ALA1140163 | assay format | Scientific Literature | ||
12. | ALA1025674 | Functional | Inhibition of LPS-induced TNFalpha production in human THP1 cells | Homo sapiens | 9 | ALA1140163 | cell-based format | Scientific Literature | |
13. | ALA1025675 | Functional | Inhibition of TNF-alpha-induced IL8 production in human whole blood cells | Homo sapiens | 9 | ALA1140163 | cell-based format | Scientific Literature | |
14. | ALA1025678 | ADME | Clearance in Sprague-Dawley rat 2 mg/kg, iv | Rattus norvegicus | 5 | ALA1140163 | organism-based format | Scientific Literature | |
15. | ALA1025679 | ADME | Volume of distribution at steady state in Sprague-Dawley rat 2 mg/kg, iv | Rattus norvegicus | 5 | ALA1140163 | organism-based format | Scientific Literature | |
16. | ALA1025680 | ADME | Half life in Sprague-Dawley rat 2 mg/kg, iv | Rattus norvegicus | 5 | ALA1140163 | organism-based format | Scientific Literature | |
17. | ALA1025681 | ADME | AUC (0 to infinity) in Sprague-Dawley rat 10 mg/kg, po | Rattus norvegicus | 5 | ALA1140163 | organism-based format | Scientific Literature | |
18. | ALA1025682 | ADME | Oral bioavailability in Sprague-Dawley rat 10 mg/kg | Rattus norvegicus | 5 | ALA1140163 | organism-based format | Scientific Literature | |
19. | ALA1025683 | Functional | Inhibition of LPS-induced TNFalpha production in Lewis rat | Rattus norvegicus | 1 | ALA1140163 | organism-based format | Scientific Literature |