1. ALA1024879 F Inhibition of Vaccinia virus DNA synthesis in by rapid plate assay Vaccinia virus 93 ALA1140145 organism-based format Scientific Literature 2. ALA1024886 F Antiviral activity against Vaccinia virus WR in BSC1 cells assessed as reduction in plaque formation up to 200 uM after 20 hrs Vaccinia virus 19 ALA1140145 organism-based format Scientific Literature 3. ALA1024887 F Antiviral activity against Vaccinia virus WR in BSC1 cells assessed as protection from virus-induced lysis of cell monolayer up to 200 uM after 20 hrs Vaccinia virus 19 ALA1140145 organism-based format Scientific Literature 4. ALA1024888 A Cytotoxicity against african green monkey BSC1 cells up to 200 uM after 20 to 120 hrs WST-1 based assay Chlorocebus aethiops 19 ALA1140145 cell-based format Scientific Literature 5. ALA1040691 F NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay Plasmodium falciparum 5,614 ALA1156829 organism-based format Novartis Malaria Screening 6. ALA1040692 F NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay Plasmodium falciparum 5,614 ALA1156829 organism-based format Novartis Malaria Screening 7. ALA1040693 T NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) Homo sapiens 5,614 ALA1156829 cell-based format Novartis Malaria Screening 8. ALA1040694 F NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. 5,614 ALA1156829 assay format Novartis Malaria Screening 9. ALA1789905 F NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells at 10uM compound concentration, determined by immuno-fluorescence. Plasmodium yoelii 4,416 ALA1789904 organism-based format Novartis Malaria Screening 10. ALA2028070 F MMV: Inhibition of Plasmodium falciparum 3D7 at 5uM compound concentration. Plasmodium falciparum 315 ALA2028040 organism-based format MMV Malaria Box 11. ALA2028071 F MMV: Inhibition of Plasmodium falciparum 3D7 (EC50). Plasmodium falciparum 317 ALA2028040 organism-based format MMV Malaria Box 12. ALA2028072 F MMV: Inhibition of Plasmodium falciparum K1 (EC50). Plasmodium falciparum 171 ALA2028040 organism-based format MMV Malaria Box 13. ALA2028073 F MMV: Inhibition of Trypanosoma cruzi (Tulahuen C4 LacZ) (Chagas in vitro). Trypanosoma cruzi 400 ALA2028040 organism-based format MMV Malaria Box 14. ALA2028074 F MMV: Inhibition of Trypanosoma brucei brucei (Squib 427) (HAT in vitro). Trypanosoma brucei brucei 400 ALA2028040 organism-based format MMV Malaria Box 15. ALA2028075 F MMV: Inhibition of Trypanosoma brucei rhodesiense (STIB 900) (HAT in vitro). Trypanosoma brucei rhodesiense 400 ALA2028040 organism-based format MMV Malaria Box 16. ALA2028076 F MMV: Inhibition of Leishmania infantum (MHOM/MA/BE/67) in vitro. Leishmania infantum 400 ALA2028040 organism-based format MMV Malaria Box 17. ALA2028077 T MMV: Cytotoxicity against human fibroblasts (MRC-5) cells. Homo sapiens 400 ALA2028040 cell-based format MMV Malaria Box 18. ALA2094261 F MMV: Screen against Mtb, single point, non replicating, at 25uM Mycobacterium tuberculosis 399 ALA2094260 organism-based format MMV Malaria Box 19. ALA2094262 F MMV: Screen against Mtb, single point, replicating, at 25uM Mycobacterium tuberculosis 399 ALA2094260 organism-based format MMV Malaria Box 20. ALA2094263 F MMV: CRC and MIC90 against Mtb (non replicating) Mycobacterium tuberculosis 55 ALA2094260 organism-based format MMV Malaria Box