# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1023822 | B | Inhibition of humanized rabbit cathepsin K Tyr61Asp and Val157Leu mutant | Homo sapiens | 6 | ALA1140150 | assay format | Scientific Literature | |
2. | ALA1023823 | B | Inhibition of rabbit cathepsin K | Oryctolagus cuniculus | 6 | ALA1140150 | single protein format | Scientific Literature | |
3. | ALA1023824 | B | Selectivity for rabbit cathepsin K over human cathepsin K | 6 | ALA1140150 | assay format | Scientific Literature | ||
4. | ALA1023825 | B | Selectivity for rabbit cathepsin K over human cathepsin B | 6 | ALA1140150 | assay format | Scientific Literature | ||
5. | ALA1023826 | B | Selectivity for rabbit cathepsin K over human cathepsin S | 6 | ALA1140150 | assay format | Scientific Literature | ||
6. | ALA1023832 | F | Inhibition of bone resorption in rabbit bone | Oryctolagus cuniculus | 6 | ALA1140150 | tissue-based format | Scientific Literature | |
7. | ALA1023833 | F | Bone resorption shift, ratio of IC50 for inhibition of bone resorption in rabbit bone to IC50 for rabbit cathepsin K | Oryctolagus cuniculus | 6 | ALA1140150 | assay format | Scientific Literature | |
8. | ALA1023834 | B | Selectivity for rabbit cathepsin K over human cathepsin C | 2 | ALA1140150 | assay format | Scientific Literature | ||
9. | ALA1023835 | B | Selectivity for rabbit cathepsin K over human cathepsin H | 2 | ALA1140150 | assay format | Scientific Literature | ||
10. | ALA1023836 | B | Selectivity for rabbit cathepsin K over human cathepsin Z | 2 | ALA1140150 | assay format | Scientific Literature | ||
11. | ALA1023837 | B | Selectivity for rabbit cathepsin K over human cathepsin V | 2 | ALA1140150 | assay format | Scientific Literature | ||
12. | ALA1023838 | B | Selectivity for rabbit cathepsin K over human cathepsin F | 2 | ALA1140150 | assay format | Scientific Literature | ||
13. | ALA1024675 | A | Oral bioavailability in rat at 10 mL/kg | Rattus norvegicus | 2 | ALA1140150 | organism-based format | Scientific Literature | |
14. | ALA1024676 | A | Clearance in rat at 10 mL/kg, po | Rattus norvegicus | 2 | ALA1140150 | organism-based format | Scientific Literature | |
15. | ALA1024677 | A | Half life in rat at 10 mL/kg, po | Rattus norvegicus | 2 | ALA1140150 | organism-based format | Scientific Literature | |
16. | ALA1024678 | A | Volume of distribution in rat at 10 mL/kg, po | Rattus norvegicus | 2 | ALA1140150 | organism-based format | Scientific Literature | |
17. | ALA1024679 | A | Oral bioavailability in dog at 5 mL/kg | Canis lupus familiaris | 2 | ALA1140150 | organism-based format | Scientific Literature | |
18. | ALA1024680 | A | Clearance in dog at 5 mL/kg, po | Canis lupus familiaris | 2 | ALA1140150 | organism-based format | Scientific Literature | |
19. | ALA1024681 | A | Half life in dog at 5 mL/kg, po | Canis lupus familiaris | 2 | ALA1140150 | organism-based format | Scientific Literature | |
20. | ALA1024682 | A | Volume of distribution in dog at 5 mL/kg, po | Canis lupus familiaris | 2 | ALA1140150 | organism-based format | Scientific Literature |