# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1027436 | Functional | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 77 | ALA1140148 | cell-based format | Scientific Literature | |
2. | ALA1027437 | Functional | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay relative to histamine | Rattus norvegicus | 76 | ALA1140148 | cell-based format | Scientific Literature | |
3. | ALA1027438 | Functional | Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Homo sapiens | 77 | ALA1140148 | cell-based format | Scientific Literature | |
4. | ALA1772151 | Binding | Displacement of [3H]histamine from human histamine H4 receptor | Homo sapiens | 48 | ALA1770114 | single protein format | Scientific Literature | |
5. | ALA1772152 | Functional | Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells assessed as effect on forskolin-induced cAMP accumulation after 6 hrs | Homo sapiens | 26 | ALA1770114 | cell-based format | Scientific Literature | |
6. | ALA1772153 | Functional | Antagonist activity at human histamine H4 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 6 hrs | Homo sapiens | 17 | ALA1770114 | cell-based format | Scientific Literature |