# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1027436 | Functional | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Rattus norvegicus | 77 | ALA1140148 | cell-based format | Scientific Literature | |
2. | ALA1027437 | Functional | Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay relative to histamine | Rattus norvegicus | 76 | ALA1140148 | cell-based format | Scientific Literature | |
3. | ALA1027438 | Functional | Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Homo sapiens | 77 | ALA1140148 | cell-based format | Scientific Literature | |
4. | ALA2378229 | Binding | Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 mins | Homo sapiens | 7 | ALA2375220 | cell-based format | Scientific Literature | |
5. | ALA3136602 | Binding | Displacement of [3H]histamine from human histamine H4 receptor E182'5.46Q mutant transfected in HEK293T cells after 1.5 hrs by liquid scintillation counting analysis | Homo sapiens | 4 | ALA3132790 | cell-based format | Scientific Literature | |
6. | ALA3136603 | Binding | Displacement of [3H]histamine from human histamine H4 receptor L175'5.39V mutant transfected in HEK293T cells after 1.5 hrs by liquid scintillation counting analysis | Homo sapiens | 4 | ALA3132790 | cell-based format | Scientific Literature | |
7. | ALA3136604 | Binding | Displacement of [3H]histamine from wild type human histamine H4 receptor transfected in HEK293T cells after 1.5 hrs by liquid scintillation counting analysis | Homo sapiens | 10 | ALA3132790 | cell-based format | Scientific Literature |