# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1009320 | Functional | Antiproliferative activity against human HN5 cells overexpressing EGFR after 3 days by methylene blue staining | Homo sapiens | 13 | ALA1139297 | cell-based format | Scientific Literature | |
2. | ALA1009321 | Functional | Antiproliferative activity against human BT474 cells overexpressing ERBb2 after 3 days by methylene blue staining | Homo sapiens | 22 | ALA1139297 | cell-based format | Scientific Literature | |
3. | ALA1009322 | Functional | Antiproliferative activity against human HFF cells after 3 days by methylene blue staining | Homo sapiens | 10 | ALA1139297 | cell-based format | Scientific Literature | |
4. | ALA1009323 | Binding | Induction of EGFR covalent modification assessed as alkylation at 0.002 mM after 3 hrs | 4 | ALA1139297 | single protein format | Scientific Literature | ||
5. | ALA1009325 | ADME | Normalized AUC in mouse at 10 mg/kg, po in methanesulfonic acid:hydroxypropyl-beta-cyclodextrin | Mus musculus | 12 | ALA1139297 | organism-based format | Scientific Literature | |
6. | ALA1009326 | Binding | Inhibition of EGFR by scintillation proximity assay | 2 | ALA1139297 | single protein format | Scientific Literature | ||
7. | ALA1009327 | Binding | Inhibition of ERBb2 by scintillation proximity assay | 2 | ALA1139297 | single protein format | Scientific Literature |