# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA963925 | Functional | Cytotoxicity against human PC3 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA1139282 | cell-based format | Scientific Literature | |
2. | ALA963926 | Functional | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA1139282 | cell-based format | Scientific Literature | |
3. | ALA4057053 | Functional | Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in presence of type 1 collagen coated surface by MTT assay | Homo sapiens | 11 | ALA4052751 | cell-based format | Scientific Literature | |
4. | ALA4057054 | Functional | Antiproliferative activity against human MIAPaCa2 cells after 48 hrs in absence of type 1 collagen coated surface by MTT assay | Homo sapiens | 3 | ALA4052751 | cell-based format | Scientific Literature | |
5. | ALA4057055 | ADME | Antiproliferative activity against HPDEC after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4052751 | cell-based format | Scientific Literature | |
6. | ALA4057056 | Unassigned | Selectivity index, ratio of IC50 for HPDEC to IC50 for human MIAPaCa2 cells | Homo sapiens | 11 | ALA4052751 | assay format | Scientific Literature | |
7. | ALA4057057 | Functional | Induction of apoptosis in human MIAPaCa2 cells assessed as increase in early apoptotic cells measured after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
8. | ALA4057058 | Functional | Induction of apoptosis in human MIAPaCa2 cells assessed as increase in late apoptotic cells at 1 to 10 uM measured after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
9. | ALA4057059 | Functional | Induction of apoptosis in human MIAPaCa2 cells assessed as necrotic cells at 1 to 10 uM measured after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
10. | ALA4057060 | Functional | Cell cycle arrest in human MIAPaCa2 cells assessed as increase in G1 phase at 1 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
11. | ALA4057061 | Functional | Cell cycle arrest in human MIAPaCa2 cells assessed as decrease in S phase at 1 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
12. | ALA4057062 | Functional | Cell cycle arrest in human MIAPaCa2 cells assessed as decrease in G1 phase at 5 to 10 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
13. | ALA4057063 | Functional | Cell cycle arrest in human MIAPaCa2 cells assessed as increase in G2 phase at 5 to 10 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
14. | ALA4057064 | Functional | Cell cycle arrest in human MIAPaCa2 cells assessed as increase in S phase at 10 uM measured after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
15. | ALA4057065 | Functional | Induction of DNA damage in human MIAPaCa2 cells assessed as formation of DNA breaks at 5 uM after 24 hrs by comet assay | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
16. | ALA4057066 | Functional | Induction of apoptosis in human MIAPaCa2 cells assessed as apoptotic cells at 5 uM measured after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
17. | ALA4057067 | Functional | Induction of DNA damage in human MIAPaCa2 cells assessed as formation of DNA breaks at 10 uM after 24 hrs by comet assay | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
18. | ALA4057068 | Functional | Induction of apoptosis in human MIAPaCa2 cells assessed as apoptotic cells at 10 uM measured after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | ALA4052751 | cell-based format | Scientific Literature | |
19. | ALA4057069 | Binding | Inhibition of CRM1-mediated nucleocytoplasmic transport of Riok2 in human HeLa cells at 1 uM after 90 mins by DAPI staining based microscopy relative to control | Homo sapiens | 2 | ALA4052751 | cell-based format | Scientific Literature | |
20. | ALA4057072 | Binding | Inhibition of CRM1-mediated nucleocytoplasmic transport of Riok2 in human HeLa cells at 0.2 uM after 90 mins by DAPI staining based microscopy relative to control | Homo sapiens | 5 | ALA4052751 | cell-based format | Scientific Literature |