# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA953166 | F | Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity | Cavia porcellus | 34 | tissue-based format | Scientific Literature | ||
2. | ALA953167 | F | Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity relative to histamine | Cavia porcellus | 33 | tissue-based format | Scientific Literature | ||
3. | ALA953171 | F | Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced positive chronotropic activity | Cavia porcellus | 22 | tissue-based format | Scientific Literature | ||
4. | ALA953173 | F | Antagonist activity at histamine H1 receptor in human U373 MG cells assessed as inhibition of histamine-induced intracellular calcium level preincubated for 15 mins prior to histamine challenge | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
5. | ALA953174 | B | Activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA953175 | B | Activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assay relative to histamine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA953176 | B | Activity at human recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA953177 | B | Activity at human recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay relative to histamine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA953178 | B | Activity at guinea pig recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay | Cavia porcellus | 5 | cell-based format | Scientific Literature | ||
10. | ALA937680 | B | Activity at guinea pig recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay relative to histamine | Cavia porcellus | 4 | cell-based format | Scientific Literature | ||
11. | ALA937681 | B | Activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai, G-beta-1-gamma-2 and RGS4 by steady-state GTPase activity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
12. | ALA937682 | B | Activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai2, G-beta-1-gamma-2 and RGS4 by steady-state GTPase activity assay relative to histamine | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA937683 | B | Activity at human recombinant histamine H4 receptor-RGS4 fusion protein expressed in Sf9 cells coexpressing Galphai2 and G-beta-1-gamma-2 by steady-state GTPase activity assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA937684 | B | Activity at human recombinant histamine H4 receptor-RGS4 fusion protein expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2 by steady-state GTPase activity assay relative to histamine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA937686 | A | Terminal half life in nude mouse plasma | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA1015352 | B | Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid scintillation counting | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
17. | ALA1015353 | B | Agonist activity at human H3 receptor expressed in insect Sf9 cells co-expressing Gialpha2, Gbeta1gamma2 and RGS4 assessed as gamma[32P]GTP binding by liquid scintillation counting | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
18. | ALA1015354 | B | Agonist activity at human H4 receptor expressed in insect Sf9 cells co-expressing RGS19 fusion protein and Gialpha2, Gbeta1gamma2 assessed as gamma[32P]GTP binding by liquid scintillation counting | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
19. | ALA1015355 | B | Antagonist activity at human H1 receptor expressed in insect Sf9 cells co-expressing RGS4 assessed as inhibition of histamine-induced gamma[32P]GTP binding by liquid scintillation counting | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
20. | ALA1015358 | B | Intrinsic activity at human H1 receptor expressed in insect Sf9 cells co-expressing RGS4 assessed as gamma[32P]GTP binding at 10 uM by liquid scintillation counting relative to histamine | Homo sapiens | 13 | cell-based format | Scientific Literature |