| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA960055 | B | Activity at GABAA alpha-1-beta-3-gamma-2 receptor expressed in oocytes assessed as stimulation of GABA-induced current at 1 uM relative to control | 3 | ALA1153371 | cell-based format | Scientific Literature | ||
| 2. | ALA960056 | B | Activity at GABAA alpha-2-beta-3-gamma-2 receptor expressed in oocytes assessed as stimulation of GABA-induced current at 1 uM relative to control | 3 | ALA1153371 | cell-based format | Scientific Literature | ||
| 3. | ALA960057 | B | Activity at GABAA alpha-3-beta-3-gamma-2 receptor expressed in oocytes assessed as stimulation of GABA-induced current at 1 uM relative to control | 3 | ALA1153371 | cell-based format | Scientific Literature | ||
| 4. | ALA960058 | B | Activity at GABAA alpha-5-beta-3-gamma-2 receptor expressed in oocytes assessed as stimulation of GABA-induced current at 1 uM relative to control | 3 | ALA1153371 | cell-based format | Scientific Literature | ||
| 5. | ALA960064 | F | Anticonvulsant activity in rat assessed as protection against maximal electroshock-induced seizure at 30 mg/kg, ip and po after 0.5 hrs | Rattus norvegicus | 3 | ALA1153371 | organism-based format | Scientific Literature | |
| 6. | ALA960067 | F | Anticonvulsant activity in rat assessed as protection against subcutaneous metrazole-induced seizure at 50 mg/kg, po after 4 hrs | Rattus norvegicus | 1 | ALA1153371 | organism-based format | Scientific Literature | |
| 7. | ALA960073 | T | Toxicity in rat assessed as motor impairment at 50 mg/kg, ip after 0.5 hrs by rotarod paradigm test | Rattus norvegicus | 4 | ALA1153371 | organism-based format | Scientific Literature | |
| 8. | ALA960074 | T | Toxicity in rat assessed as motor impairment at 50 mg/kg, ip after 4 hrs by rotarod paradigm test | Rattus norvegicus | 3 | ALA1153371 | organism-based format | Scientific Literature | |
| 9. | ALA960077 | F | Anticonvulsant activity in ip dosed mouse assessed as protection against maximal electroshock-induced seizure | Mus musculus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 10. | ALA960078 | F | Anticonvulsant activity in ip dosed mouse assessed as protection against subcutaneous metrazole-induced seizure | Mus musculus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 11. | ALA960079 | T | Toxicity in ip dosed mouse assessed as minimal muscular or neurological impairment by rotarod paradigm test | Mus musculus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 12. | ALA960080 | F | Anticonvulsant activity in po dosed rat assessed as protection against maximal electroshock-induced seizure | Rattus norvegicus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 13. | ALA960081 | F | Anticonvulsant activity in po dosed rat assessed as protection against subcutaneous metrazole-induced seizure | Rattus norvegicus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 14. | ALA960082 | T | Toxicity in po dosed rat assessed as minimal muscular or neurological impairment by rotarod paradigm test | Rattus norvegicus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 15. | ALA960875 | A | Therapeutic index, ratio of TD50 for ip dosed mouse to ED50 for protection against subcutaneous metrazole-induced seizure in ip dosed mouse | Mus musculus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 16. | ALA960876 | A | Therapeutic index, ratio of TD50 for po dosed rat to ED50 for protection against subcutaneous metrazole-induced seizure in po dosed rat | Rattus norvegicus | 6 | ALA1153371 | organism-based format | Scientific Literature | |
| 17. | ALA960879 | F | Anticonvulsant activity in rat assessed as blockade against kindle motor-induced seizure at 50 mg/kg, ip by hippocampal kindling screen test | Rattus norvegicus | 1 | ALA1153371 | organism-based format | Scientific Literature | |
| 18. | ALA960882 | F | Anticonvulsant activity against kindle motor-induced seizure in rat assessed as after discharge duration at 50 mg/kg, ip by hippocampal kindling screen test | Rattus norvegicus | 1 | ALA1153371 | organism-based format | Scientific Literature | |
| 19. | ALA960884 | T | Toxicity in rat assessed as motor impairment at 30 mg/kg, ip after 1 hr by rotarod paradigm test | Rattus norvegicus | 2 | ALA1153371 | organism-based format | Scientific Literature | |
| 20. | ALA2341048 | A | Metabolic stability in heat inactivated human liver microsomes assessed as compound remaining at 10 uM measured at 60 mins by LC-MS/MS analysis relative to control | Homo sapiens | 10 | ALA2331169 | microsome format | Scientific Literature |
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