| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA960886 | F | Inhibition of human recombinant MMP-12-induced lung inflammation in C57BL/6 mouse chronic obstructive pulmonary disease model assessed as inhibition of bronchoalveolar lavage fluid inflammation at 30 mg/kg, po qd | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA960887 | B | Inhibition of human recombinant MMP12 expressed in Escherichia coli | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 3. | ALA960888 | B | Inhibition of human MMP1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA960889 | B | Inhibition of sheep MMP12 | Ovis aries | 1 | assay format | Scientific Literature | ||
| 5. | ALA960890 | B | Inhibition of rat MMP12 | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 6. | ALA960891 | B | Inhibition of mouse recombinant MMP12 | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 7. | ALA960892 | B | Inhibition of human recombinant MMP13 expressed in Escherichia coli | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 8. | ALA960894 | A | Volume of distribution at steady state in C57BL/6 mouse at 2 mg/kg, iv | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 9. | ALA960895 | A | Clearance in C57BL/6 mouse at 2 mg/kg, iv | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 10. | ALA960896 | A | Half life in C57BL/6 mouse at 30 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA958324 | A | Cmax in C57BL/6 mouse at 30 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA958325 | A | AUC in C57BL/6 mouse at 30 mg/kg, po | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA958326 | A | Oral bioavailability in C57BL/6 mouse at 30 mg/kg | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA958327 | B | Inhibition of human MMP3 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA958328 | B | Inhibition of human MMP7 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA958329 | B | Inhibition of human MMP9 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA958330 | B | Inhibition of human TACE | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA958331 | B | Inhibition of human Aggrecanase-1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA958332 | B | Inhibition of human Aggrecanase-2 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA958333 | B | Inhibition of human MMP14 | Homo sapiens | 1 | single protein format | Scientific Literature |
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