| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1016136 | B | Inhibition of Plasmodium berghei ANKA DHODH | Plasmodium berghei | 40 | organism-based format | Scientific Literature | ||
| 2. | ALA1016137 | B | Inhibition of human DHODH | Homo sapiens | 40 | single protein format | Scientific Literature | ||
| 3. | ALA1016138 | F | Antiplasmodial activity against Plasmodium falciparum 3D7 by [3H]hypoxanthine uptake | Plasmodium falciparum | 40 | organism-based format | Scientific Literature | ||
| 4. | ALA1016139 | A | Metabolic stability in human liver microsomes assessed as degradation half life at 1 uM | Homo sapiens | 14 | microsome format | Scientific Literature | ||
| 5. | ALA1016140 | A | Intrinsic clearance in human liver microsomes at 1 uM | Homo sapiens | 14 | microsome format | Scientific Literature | ||
| 6. | ALA1016143 | A | Plasma concentration in Swiss mouse at 20 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA1016144 | A | Plasma concentration in Swiss mouse at 50 mg/kg, po administered as single dose for 16 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1016145 | A | Half life in Swiss mouse at 20 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1016146 | A | Half life in Swiss mouse at 50 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA1016147 | A | Cmax in Swiss mouse at 20 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1016148 | A | Cmax in Swiss mouse at 50 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA1016149 | A | AUC (0 to last) in Swiss mouse at 20 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA1016150 | A | AUC (0 to last) in Swiss mouse at 50 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA1016151 | T | Toxicity in Plasmodium berghei NK65 infected BALB/c mice (Mus musculus) at 50 mg/kg, perorally qd for 4 days measured on day 5 postinfection | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA1016152 | F | Antimalarial activity as reduced growth at day 5 in Plasmodium berghei NK65 infected BALB/c mice (Mus musculus) at 50 mg/kg peroral dose over 4 days | Plasmodium berghei | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA1016153 | F | Antimalarial activity as reduced growth at day 5 in Plasmodium berghei NK65 infected BALB/c mice (Mus musculus) at 50 mg/kg peroral dose over 4 days | Plasmodium berghei | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA1016154 | B | Inhibition of Plasmodium falciparum DHODH | Plasmodium falciparum | 40 | single protein format | Scientific Literature | ||
| 18. | ALA1016156 | T | Toxicity in Plasmodium berghei NK65 infected BALB/c mice (Mus musculus) at 50 mg/kg, perorally bid for 4 days measured on day 5 postinfection | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA1016158 | T | Toxicity in Swiss mouse at 50 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA1016159 | T | Toxicity in Swiss mouse at 20 mg/kg, po administered as single dose | Mus musculus | 1 | organism-based format | Scientific Literature |
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