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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA660957 B DNA binding affinity at low ionic strength as change in midpoint Bos taurus 32 nucleic acid format Scientific Literature 2. ALA788514 F Ability to reduce the severity of PCP in immunosuppressed rats after (iv) administration of 10 mg/kg/day Pneumocystis carinii 30 organism-based format Scientific Literature 3. ALA788515 F Ability to reduce the severity of PCP in immunosuppressed rats after (i.v.) administration of 10 mg/kg/day Pneumocystis carinii 21 organism-based format Scientific Literature 4. ALA788518 F Ability to reduce the severity of PCP in immunosuppressed rats after (iv) administration of 10 mg/kg/day Pneumocystis carinii 31 organism-based format Scientific Literature 5. ALA811651 A Cytotoxicity in lung, spleen and kidneys for pathologic changes by light microscopy.++ = most animals survived, some with severe distress and marked local toxicity and some systemic toxicity and histopathologic abnormalities Rattus norvegicus 1 tissue-based format Scientific Literature 6. ALA815012 B Inhibition of trypsin by amidase assay. 28 single protein format Scientific Literature 7. ALA960936 A Cytotoxicity against rat L6 cells after 70 hrs by alamar blue assay Rattus norvegicus 70 cell-based format Scientific Literature 8. ALA960937 F Antiprotozoal activity against Trypanosoma brucei rhodesiense STIB900 trypomastigotes after 70 hrs by alamar blue assay Trypanosoma brucei rhodesiense 67 organism-based format Scientific Literature 9. ALA961732 T Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma brucei rhodesiense STIB900 trypomastigotes 67 cell-based format Scientific Literature 10. ALA961733 F Antiprotozoal activity after 48 hrs against chloroquine-resistant Plasmodium falciparum K1 infected erythrocytes by [3H]hypoxanthine uptake Plasmodium falciparum 68 organism-based format Scientific Literature 11. ALA961734 T Selectivity index, ratio of IC50 for rat L6 cells to IC50 for chloroquine-resistant Plasmodium falciparum K1 68 cell-based format Scientific Literature 12. ALA961735 F Antiprotozoal activity against Leishmania donovani MHOM/SD/62/1S-CL2D axenic amastigotes after 72 hrs Leishmania donovani 66 organism-based format Scientific Literature 13. ALA961736 T Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Leishmania donovani MHOM/SD/62/1S-CL2D axenic amastigotes 66 cell-based format Scientific Literature 14. ALA957600 F Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 trypomastigotes infected in NMRI mouse assessed as mouse survival at 20 mg/kg, ip administered from day 3 to day 6 postinfection Trypanosoma brucei rhodesiense 20 organism-based format Scientific Literature 15. ALA957601 F Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 trypomastigotes infected in NMRI mouse assessed as mouse survival at 10 mg/kg, ip administered from day 3 to day 6 postinfection Trypanosoma brucei rhodesiense 12 organism-based format Scientific Literature 16. ALA1054500 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM Plasmodium falciparum 13,467 organism-based format GSK Malaria Screening 17. ALA1054501 F GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM Plasmodium falciparum 13,467 organism-based format GSK Malaria Screening 18. ALA1054502 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM Plasmodium falciparum 13,467 organism-based format GSK Malaria Screening 19. ALA1054503 F GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. Plasmodium falciparum 13,467 organism-based format GSK Malaria Screening 20. ALA1054504 F GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. Homo sapiens 13,467 cell-based format GSK Malaria Screening