# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3807134 | Binding | Inhibition of DAAO in porcine kidney homogenate using D-alanine as substrate assessed as pyruvate production incubated for 5 mins by microplate reader analysis | Sus scrofa | 36 | ALA3804792 | assay format | Scientific Literature | |
2. | ALA3807135 | Binding | Inhibition of rat spinal DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysis | Rattus norvegicus | 7 | ALA3804792 | single protein format | Scientific Literature | |
3. | ALA3807136 | Binding | Inhibition of human recombinant DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysis | Homo sapiens | 7 | ALA3804792 | single protein format | Scientific Literature | |
4. | ALA1794345 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | ALA1201862 | organism-based format | PubChem BioAssays | |
5. | ALA1794401 | Functional | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | 91,504 | ALA1201862 | assay format | PubChem BioAssays | ||
6. | ALA1832105 | Binding | Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescence assay | Homo sapiens | 6 | ALA1828557 | assay format | Scientific Literature | |
7. | ALA1832107 | Binding | Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysis | Homo sapiens | 6 | ALA1828557 | single protein format | Scientific Literature | |
8. | ALA1832108 | Binding | Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assay | Homo sapiens | 6 | ALA1828557 | single protein format | Scientific Literature | |
9. | ALA1832109 | Binding | Binding affinity to human recombinant DAAO by steady state study scintillation proximity assay | Homo sapiens | 6 | ALA1828557 | single protein format | Scientific Literature | |
10. | ALA1832110 | Binding | Inhibition of bovine recombinant DASPO expressed in Escherichia coli preincubated for 15 mins by fluorescence assay | Bos taurus | 6 | ALA1828557 | assay format | Scientific Literature | |
11. | ALA1832111 | Binding | Inhibition of human ERG expressed in HEK293 cells by whole cell voltage patch clamp technique | Homo sapiens | 6 | ALA1828557 | cell-based format | Scientific Literature | |
12. | ALA1832112 | Binding | Binding affinity to human recombinant DAAO assessed as drug-enzyme complex half life | Homo sapiens | 6 | ALA1828557 | single protein format | Scientific Literature | |
13. | ALA1832113 | Physicochemical | Dissociation constant, pKa of the compound by dip probe absorption spectroscopy technique | 6 | ALA1828557 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA1832114 | Physicochemical | Octanol-water partition coefficient, log P of the neutral compound by pH-metric method | 6 | ALA1828557 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA1832116 | Physicochemical | Thermodynamic solubility of the compound in phosphate buffer at pH 7.4 after 24 hrs by HPLC analysis | 6 | ALA1828557 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA1832117 | Physicochemical | Kinetic solubility of the compound in 0.01 M phosphate buffered saline at pH 7.4 assessed as minimum solubility after 2 hrs | 6 | ALA1828557 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA1832118 | Physicochemical | Kinetic solubility of the compound in 0.01 M phosphate buffered saline at pH 7.4 assessed as maximum solubility after 2 hrs | 6 | ALA1828557 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA1832119 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells by LC-MS/MS analysis | Homo sapiens | 2 | ALA1828557 | cell-based format | Scientific Literature | |
19. | ALA1832120 | ADME | Apparent permeability from apical to basolateral side of MDCK cells expressing MDR1 by LC-MS/MS analysis | Canis lupus familiaris | 2 | ALA1828557 | cell-based format | Scientific Literature | |
20. | ALA1832264 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in human Caco2 cells by LC-MS/MS analysis | Homo sapiens | 2 | ALA1828557 | cell-based format | Scientific Literature |