| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1653933 | Functional | Antiparasitic activity against Trypanosoma brucei rhodesiense STIB 900 clone after 72 hrs by Alamar blue assay | Trypanosoma brucei rhodesiense | 5 | ALA1649443 | organism-based format | Scientific Literature | |
| 2. | ALA1653934 | Binding | Ratio of Kinact to Kiapp for Trypanosoma brucei AdoMetDC expressed in Escherichia coli | Trypanosoma brucei | 5 | ALA1649443 | assay format | Scientific Literature | |
| 3. | ALA1653935 | Binding | Ratio of Kinact to Kiapp for human AdoMetDC expressed in Escherichia coli | Homo sapiens | 5 | ALA1649443 | assay format | Scientific Literature | |
| 4. | ALA1653936 | Physicochemical | Kinetic solubility in dimethyl sulfoxide at pH 7.4 after 16 to 24 hrs by UV spectrophotometry | 5 | ALA1649443 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA1653937 | ADME | Permeability of the compound after 4 hrs by PAMPA assay | 5 | ALA1649443 | assay format | Scientific Literature | ||
| 6. | ALA1653938 | ADME | Metabolic stability in rat liver microsomes assessed as intrinsic clearance up to 45 mins by LC/MS/MS analysis | Rattus norvegicus | 5 | ALA1649443 | microsome format | Scientific Literature | |
| 7. | ALA1653939 | ADME | Metabolic stability in human liver microsomes assessed as intrinsic clearance up to 45 mins by LC/MS/MS analysis | Homo sapiens | 5 | ALA1649443 | microsome format | Scientific Literature | |
| 8. | ALA1653940 | ADME | Metabolic stability in rat hepatocytes assessed as intrinsic clearance up to 45 mins by LC/MS/MS analysis | Rattus norvegicus | 5 | ALA1649443 | cell-based format | Scientific Literature | |
| 9. | ALA1653941 | ADME | Metabolic stability in human hepatocytes assessed as intrinsic clearance up to 45 mins by LC/MS/MS analysis | Homo sapiens | 5 | ALA1649443 | cell-based format | Scientific Literature | |
| 10. | ALA1653942 | ADME | Inhibition of human cytochrome P450 3A4 | Homo sapiens | 5 | ALA1649443 | single protein format | Scientific Literature | |
| 11. | ALA1653943 | ADME | Inhibition of human cytochrome P450 2D6 | Homo sapiens | 5 | ALA1649443 | single protein format | Scientific Literature | |
| 12. | ALA1653944 | ADME | Inhibition of human cytochrome P450 2C9 | Homo sapiens | 5 | ALA1649443 | single protein format | Scientific Literature | |
| 13. | ALA1653945 | ADME | Inhibition of human cytochrome P450 2C19 | Homo sapiens | 5 | ALA1649443 | single protein format | Scientific Literature | |
| 14. | ALA1653946 | ADME | Inhibition of human cytochrome P450 1A2 | Homo sapiens | 5 | ALA1649443 | single protein format | Scientific Literature | |
| 15. | ALA1653947 | ADME | Protein binding in human plasma at pH 7.4 after 4 hrs | Homo sapiens | 5 | ALA1649443 | cell-free format | Scientific Literature | |
| 16. | ALA1653948 | ADME | Protein binding in mouse plasma at pH 7.4 after 4 hrs | Mus musculus | 5 | ALA1649443 | cell-free format | Scientific Literature | |
| 17. | ALA1654083 | ADME | AUC in mouse blood at 50 mg/kg, ip administered as single dose | Mus musculus | 4 | ALA1649443 | organism-based format | Scientific Literature | |
| 18. | ALA1654084 | ADME | AUC in mouse brain at 50 mg/kg, ip administered as single dose | Mus musculus | 4 | ALA1649443 | organism-based format | Scientific Literature | |
| 19. | ALA1654085 | ADME | Half life in mouse at 50 mg/kg, ip administered as single dose | Mus musculus | 4 | ALA1649443 | organism-based format | Scientific Literature | |
| 20. | ALA1654086 | ADME | Ratio of AUC in brain to blood for mouse at 50 mg/kg, ip administered as single dose | Mus musculus | 4 | ALA1649443 | organism-based format | Scientific Literature |
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