# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA980690 | Binding | Inhibition of aggrecanase1 | 30 | ALA1138597 | single protein format | Scientific Literature | ||
2. | ALA980692 | Binding | Inhibition of MMP1 | 4 | ALA1138597 | single protein format | Scientific Literature | ||
3. | ALA980693 | Binding | Inhibition of MMP2 | 4 | ALA1138597 | single protein format | Scientific Literature | ||
4. | ALA980694 | Binding | Inhibition of MMP13 | 4 | ALA1138597 | single protein format | Scientific Literature | ||
5. | ALA980695 | Binding | Inhibition of MMP14 | 4 | ALA1138597 | single protein format | Scientific Literature | ||
6. | ALA980696 | Binding | Inhibition of IL1-induced aggrecanase activity in bovine cartilage explant assessed as release of degraded extracellular matrix aggrecan | Bos taurus | 4 | ALA1138597 | single protein format | Scientific Literature | |
7. | ALA980697 | Binding | Inhibition of IL1-induced aggrecanase activity in bovine cartilage explant assessed as inhibition of proteoglycan degradation at 10 ug/ml after 3 days | Bos taurus | 4 | ALA1138597 | single protein format | Scientific Literature | |
8. | ALA980698 | ADME | Clearance in Sprague-Dawley rat at 2 mg/kg, iv or 25 mg/kg, po | Rattus norvegicus | 1 | ALA1138597 | organism-based format | Scientific Literature | |
9. | ALA980699 | ADME | Oral bioavailability in Sprague-Dawley rat at 25 mg/kg | Rattus norvegicus | 1 | ALA1138597 | organism-based format | Scientific Literature | |
10. | ALA966871 | ADME | Half life in Sprague-Dawley rat at 2 mg/kg, iv or 25 mg/kg, po | Rattus norvegicus | 1 | ALA1138597 | organism-based format | Scientific Literature | |
11. | ALA966872 | ADME | Cmax in Sprague-Dawley rat at 2 mg/kg, iv or 25 mg/kg, po | Rattus norvegicus | 1 | ALA1138597 | organism-based format | Scientific Literature | |
12. | ALA966873 | Binding | Inhibition of aggrecanase2 | 3 | ALA1138597 | single protein format | Scientific Literature |