Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of 8-isoprostane level in serum at 10 uM treated intranasally by immunoassay
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as plasma histamine release at 0.1 uM treated intranasally after 5 mins by immunoassay
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as inhibition of tryptase-like protease activity in BAL fluid using tosyl-gly pros-lys-pNA as substrate at 100 nM after 1 hr relative to control
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as inhibition of tryptase-like protease activity in BAL fluid using tosyl-gly pros-lys-pNA as substrate after 1 hr
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as inhibition of airway remodeling at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge measured on day 71
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of area of proliferating smooth muscle cell at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge measured on day 71 by PCNA+-staining
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of decrease in smooth muscle area at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge measured on day 71 by alpha-SMA-staining
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of collagen and old fibrin at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge measured on day 71 by martius scarlet blue-staining
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of methacholine-induced airway hyperreactivity at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge measured on day 71
Antiasthmatic activity in OVA-immunized BALB/c mouse chronic asthma model assessed as reduction of airway inflammation at 100 nM treated intranasally on days 15, 16, 22, and 23 at 30 mins before OVA challenge by hematoxylin and eosin staining measured on day 71