# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA996578 | Functional | Cytotoxicity against human HT-29 cells by MTT assay | Homo sapiens | 5 | ALA1150886 | cell-based format | Scientific Literature | |
2. | ALA996579 | Functional | Cytotoxicity against human A549 cells by MTT assay | Homo sapiens | 5 | ALA1150886 | cell-based format | Scientific Literature | |
3. | ALA3243631 | Functional | Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
4. | ALA3243632 | Functional | Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
5. | ALA3243633 | ADME | Cytotoxicity against tumor promotion-sensitive mouse JB6 Cl41 cells assessed as cell viability after 48 hrs by MTS assay | Mus musculus | 11 | ALA3232964 | cell-based format | Scientific Literature | |
6. | ALA3243634 | Functional | Cytotoxicity against human HeLa cells assessed as inhibition of number of colonies formed in soft agar after 14 days by microscopic analysis | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
7. | ALA3243635 | Functional | Ratio of IC50 to INCC50 for human HeLa cells | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
8. | ALA3243361 | Binding | Inhibition of p53-dependent transcriptional activity in tumor promotion-sensitive mouse JB6 Cl41 cells after 12 hrs by luciferase-based method | Mus musculus | 11 | ALA3232964 | cell-based format | Scientific Literature | |
9. | ALA2209271 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | Mycobacterium tuberculosis | 67 | ALA2203104 | organism-based format | Scientific Literature | |
10. | ALA2379464 | Functional | Antitumor activity against mouse H22 cells allografted in Kunming mouse assessed as decrease in tumor size at 0.5 to 1 mg/kg/day, ip administered 8 days measured after 10 days | Mus musculus | 1 | ALA2375211 | organism-based format | Scientific Literature | |
11. | ALA2379487 | Toxicity | Toxicity in Kunming mouse allografted with mouse H22 cells assessed as decrease in body weight at 0.25 to 1 mg/kg/day, ip measured every day for 8 days | Mus musculus | 1 | ALA2375211 | organism-based format | Scientific Literature | |
12. | ALA2379490 | Functional | Antitumor activity against mouse H22 cells allografted in Kunming mouse assessed as decrease in weight of tumor mass at 1 mg/kg/day, ip administered 8 days measured after 10 days relative to control | Mus musculus | 1 | ALA2375211 | organism-based format | Scientific Literature | |
13. | ALA2379491 | Functional | Antitumor activity against mouse H22 cells allografted in Kunming mouse assessed as decrease in weight of tumor mass at 0.5 mg/kg/day, ip administered 8 days measured after 10 days relative to control | Mus musculus | 1 | ALA2375211 | organism-based format | Scientific Literature | |
14. | ALA2379492 | Functional | Induction of apoptosis in human HepG2 cells assessed as decrease in Bcl-2 level at 1.6 to 4.8 ug/mL after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
15. | ALA2379493 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in Bax level after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
16. | ALA2379494 | Functional | Induction of apoptosis in human HepG2 cells assessed as PARP cleavage at 1.6 to 4.8 ug/mL after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
17. | ALA2379495 | Functional | Induction of apoptosis in human HepG2 cells assessed as mitochondrial cytochrome c-dependent caspase-3 activation at 1.6 to 4.8 ug/mL after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
18. | ALA2379496 | Functional | Induction of apoptosis in human HepG2 cells assessed as mitochondrial cytochrome c-dependent caspase-9 activation at 1.6 to 4.8 ug/mL after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
19. | ALA2379497 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in mitochondrial cytochrome c release after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature | |
20. | ALA2379498 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in early apoptotic cells after 24 hrs by annexin V-FITC/propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 1 | ALA2375211 | cell-based format | Scientific Literature |