| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1769371 | Functional | Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay | Homo sapiens | 11 | ALA1764966 | cell-based format | Scientific Literature | |
| 2. | ALA1769372 | Functional | Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay | Homo sapiens | 11 | ALA1764966 | cell-based format | Scientific Literature | |
| 3. | ALA1769373 | Functional | Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 11 | ALA1764966 | cell-based format | Scientific Literature | |
| 4. | ALA1036083 | Functional | Insecticidal activity against Ctenocephalides felis by anti-flea artificial membrane feeding system | Ctenocephalides felis | 5 | ALA1146481 | organism-based format | Scientific Literature | |
| 5. | ALA2175762 | Binding | Inhibition of Drosophila MthB expressed in HEK293 cells assessed as inhibition of SunA1-30-induced calcium influx incubated for 10 mins prior to SunA1-30 addition by Fluo-4-AM based fluorimetry | Drosophila | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 6. | ALA2175763 | Functional | Inhibition of adrenergic receptor 1a expressed in HEK293 cells assessed as inhibition of calcium influx after 10 mins by Fluo-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 7. | ALA2175764 | Functional | Inhibition of adrenergic receptor 1b receptor expressed in HEK293 cells assessed as inhibition of calcium influx after 10 mins by Fluo-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 8. | ALA2175765 | Functional | Inhibition of CCR6 expressed in HEK293 cells assessed as inhibition of calcium influx after 10 mins by Fluo-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 9. | ALA2175766 | Functional | Inhibition of GCGR expressed in HEK293 cells assessed as inhibition of calcium influx after 10 mins by Fluo-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 10. | ALA2175767 | Functional | Agonist activity at GCGR expressed in HEK293 cells assessed as calcium influx at 1 uM by Fluor-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 11. | ALA2175769 | Functional | Induction of GCGR desensitization expressed in HEK293 cells assessed as reduction in glucagon-induced calcium influx at 1 uM incubated for 30 mins prior to glucagon-induction by Fluo-4-AM based fluorimetry | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 12. | ALA2175771 | Binding | Activation of pDsRed-tagged GCGR expressed in HEK293 cells assessed as receptor internalization at 1 uM incubated after 30 mins by Hoechst staining-based fluorescence microscopy | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 13. | ALA2175773 | Binding | Induction of PKC phosphorylation in HEK293 cells at 1 uM by Western blot analysis | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 14. | ALA2175774 | Binding | Induction of PKC phosphorylation in HEK293 cells at 1 uM by Western blot analysis in presence of GF109203 X | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 15. | ALA2175775 | Binding | Induction of PKC phosphorylation in HEK293 cells at 1 uM by Western blot analysis in presence of rotterin | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 16. | ALA2175776 | Binding | Activation of human GFP-tagged PKCalpha expressed in HEK293 cells assessed as translocation from cytoplasm to membrane at 1 uM after 30 mins by Hoechst staining-based fluorescence microscopy | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 17. | ALA2175777 | Binding | Activation of human GFP-tagged PKCalpha expressed in HEK293 cells assessed as translocation from cytoplasm to membrane at 1 uM after 30 mins by Hoechst staining-based fluorescence microscopy in presence of GF109203X | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 18. | ALA2175778 | Functional | Agonist activity at GCGR expressed in HEK293 cells assessed as calcium influx at 1 uM by Fluor-4-AM based fluorimetry in presence of GF109203X | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 19. | ALA2175780 | Functional | Induction of GCGR desensitization expressed in HEK293 cells assessed as reduction in glucagon-induced calcium influx at 1 uM incubated for 30 mins prior to glucagon-induction by Fluo-4-AM based fluorimetry in presence of GF109203X | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature | |
| 20. | ALA2175781 | Functional | Induction of GCGR desensitization expressed in HEK293 cells assessed as reduction in glucagon-induced calcium influx at 1 uM incubated for 30 mins prior to glucagon-induction by Fluo-4-AM based fluorimetry in presence of rottlerin | Homo sapiens | 1 | ALA2169797 | cell-based format | Scientific Literature |
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