| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1036086 | F | Immunosuppressive activity in lymphocytes by mixed lymphocyte reaction assay | 2 | cell-based format | Scientific Literature | |||
| 2. | ALA1036087 | F | Immunosuppressive activity in thymocytes by thymocyte proliferation assay | 2 | cell-based format | Scientific Literature | |||
| 3. | ALA3364730 | F | Immunosuppressive activity in C57Bl/6 mouse lymphocytes assessed as inhibition of cell proliferation co-incubated with BALB/c mouse stimulator lymphocytes after 72 hrs by [3H]-thymidine incorporation assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3364731 | F | Immunosuppressive activity in mouse thymocytes assessed as inhibition of IL-1-induced cell proliferation for 72 hrs by [3H]thymidine incorporation assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3364732 | F | Induction of apoptosis in pMel-1 TCR transgenic C57BL/6 mouse gp100 (25 to 33)-activated CD8-positive T cells assessed as live divided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 55.2%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3364733 | F | Induction of apoptosis in pMel-1 TCR transgenic C57BL/6 mouse gp100 (25 to 33)-activated CD8-positive T cells assessed as live undivided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 23.4%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3364734 | F | Induction of apoptosis in pMel-1 TCR transgenic C57BL/6 mouse gp100 (25 to 33)-activated CD8-positive T cells assessed as dead undivided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 6.77%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3364735 | F | Induction of apoptosis in pMel-1 TCR transgenic C57BL/6 mouse gp100 (25 to 33)-activated CD8-positive T cells assessed as dead divided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 14.7%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3364736 | F | Induction of apoptosis in LLO118 TCR transgenic mouse LLO (190 to 205)-activated CD4-positive T cells assessed as live divided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 40.6%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3364737 | F | Induction of apoptosis in LLO118 TCR transgenic mouse LLO (190 to 205)-activated CD4-positive T cells assessed as live undivided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 41.6%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3362861 | F | Induction of apoptosis in LLO118 TCR transgenic mouse LLO (190 to 205)-activated CD4-positive T cells assessed as dead undivided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 14.7%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3362862 | F | Induction of apoptosis in LLO118 TCR transgenic mouse LLO (190 to 205)-activated CD4-positive T cells assessed as dead divided cells at 100 nM after 48 hrs by CFSE dilution/flow cytometric analysis (Rvb = 3.04%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3362864 | F | Antiinflammatory activity in LLO118 TCR transgenic mouse IL-2-competent CD4-positive T cells assessed as inhibition of LLO (190 to 205)-induced IL-2 production at 1 nM for 2 days by flow cytometric analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3362865 | F | Antiinflammatory activity in LLO118 TCR transgenic mouse IL-2-competent CD4-positive T cells assessed as inhibition of LLO (190 to 205)-induced IL-2 production at 100 nM for 2 days by flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3362866 | F | Antiinflammatory activity in LLO118 TCR transgenic mouse Th1 cells assessed as inhibition of IFN-gamma production at 10 nM for 2 days by flow cytometric analysis (Rvb = 90%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3362868 | F | Antiinflammatory activity in LLO118 TCR transgenic mouse Th17 cells assessed as inhibition of IL-17 production at 10 to 100 nM for 2 days by flow cytometric analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3362869 | F | Reduction in mitochondrial mass in LLO118 TCR transgenic mouse Th1 cells at 50 to 100 nM for 2 days by MitoTracker Deep Red FM staining-based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3362870 | F | Reduction in mitochondrial mass in LLO118 TCR transgenic mouse Th17 cells at 50 to 100 nM for 2 days by MitoTracker Deep Red FM staining-based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3362871 | F | Induction of mitochondrial depolarization in LLO118 TCR transgenic mouse Th1 cells treated for 2 days by MitoTracker Orange CMTMRos staining-based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3362872 | F | Induction of mitochondrial depolarization in LLO118 TCR transgenic mouse Th17 cells treated for 2 days by MitoTracker Orange CMTMRos staining-based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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