# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3541985 | ADME | Cellular uptake in HEK293 cells assessed as bovine OATP1A2-mediated drug uptake at 100 nM by liquid scintillation counting | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature | |
2. | ALA3541987 | ADME | Cellular uptake in HEK293 cells assessed as bovine OATP1A2-mediated drug uptake at 100 nM up to 2 mins by liquid scintillation counting | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature | |
3. | ALA3542040 | ADME | Apparent permeability from basolateral to apical side of MRP2 knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 6 | ALA3525968 | cell-based format | Scientific Literature | |
4. | ALA3542041 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in vector transfected human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 3 | ALA3525968 | cell-based format | Scientific Literature | |
5. | ALA3542042 | ADME | Apparent permeability from apical to basolateral side of P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
6. | ALA3542043 | ADME | Apparent permeability from basolateral to apical side of P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 5 | ALA3525968 | cell-based format | Scientific Literature | |
7. | ALA3542044 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
8. | ALA3542045 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis relative to vector transfected cells | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
9. | ALA3542046 | ADME | Apparent permeability from apical to basolateral side of BCRP knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
10. | ALA3542047 | ADME | Apparent permeability from basolateral to apical side of BCRP knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 5 | ALA3525968 | cell-based format | Scientific Literature | |
11. | ALA3542048 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in BCRP knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
12. | ALA3542049 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in BCRP knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis relative to vector transfected cells | Homo sapiens | 2 | ALA3525968 | cell-based format | Scientific Literature | |
13. | ALA3542050 | ADME | Apparent permeability from apical to basolateral side of MRP2 knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 3 | ALA3525968 | cell-based format | Scientific Literature | |
14. | ALA3542051 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MRP2 knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis | Homo sapiens | 3 | ALA3525968 | cell-based format | Scientific Literature | |
15. | ALA3537190 | ADME | Efflux ratio of permeability from apical to basolateral over basolateral to apical side in MRP2 knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis relative to vector transfected cells | Homo sapiens | 3 | ALA3525968 | cell-based format | Scientific Literature | |
16. | ALA3538497 | ADME | Cellular uptake in HEK293 cells assessed as bovine high affinity site of OATP1A2-mediated drug uptake at 0.01 to 50 uM after 1 min by Eadie-Hofstee plot analysis | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature | |
17. | ALA3538498 | ADME | Cellular uptake in HEK293 cells assessed as bovine low affinity site of OATP1A2-mediated drug uptake at 0.01 to 50 uM after 1 min by Eadie-Hofstee plot analysis | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature | |
18. | ALA3538499 | ADME | Cellular uptake in HEK293 cells assessed as human OATP1A2-mediated drug uptake at 0.05 uM after 1 min by Eadie-Hofstee plot analysis | Homo sapiens | 2 | ALA3525993 | cell-based format | Scientific Literature | |
19. | ALA3538501 | ADME | Cellular uptake in HEK293 cells assessed as bovine high affinity site of OATP1A2-mediated drug uptake at 50 nM at pH 6 after 1 min | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature | |
20. | ALA3538502 | ADME | Cellular uptake in HEK293 cells assessed as bovine high affinity site of OATP1A2-mediated drug uptake at 50 nM at pH 7.4 after 1 min | Bos taurus | 1 | ALA3525993 | cell-based format | Scientific Literature |