# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA972348 | Binding | Displacement of [125I]GLP1 from human GLP1R expressed in CHOK1 cells | Homo sapiens | 21 | ALA1150266 | cell-based format | Scientific Literature | |
2. | ALA972349 | Functional | Agonist activity at human GLP1R expressed in CHO cells assessed as increase in cAMP level by cAMP-response element/luciferase activation assay | Homo sapiens | 21 | ALA1150266 | cell-based format | Scientific Literature | |
3. | ALA972350 | ADME | Stability in human plasma at 1000 ng/mL at 37 degC | Homo sapiens | 6 | ALA1150266 | cell-free format | Scientific Literature | |
4. | ALA3994844 | Binding | Displacement of [125I]-GLP (7 to 36 residues) from human GLP1R expressed in CHO cell membranes incubated for 30 mins measured after 10 hrs by scintillation proximity assay | Homo sapiens | 29 | ALA3994575 | cell-based format | Scientific Literature | |
5. | ALA3994845 | Functional | Agonist activity at human GLP1R expressed in CHO cells assessed as cAMP accumulation incubated for 30 mins by LANCE assay | Homo sapiens | 31 | ALA3994575 | cell-based format | Scientific Literature | |
6. | ALA3994846 | Binding | Agonist activity at human GLP1R expressed in CHOK1 cells assessed as induction of beta-galactosidase-tagged beta-arrestin2 recruitment incubated for 90 mins by PathHunter enzyme complementation assay | Homo sapiens | 30 | ALA3994575 | cell-based format | Scientific Literature | |
7. | ALA3994847 | Binding | Agonist activity at GLP1R in rat INS-1 cells assessed as increase in glucose-stimulated insulin secretion after 1 hr by HTRF assay | Rattus norvegicus | 7 | ALA3994575 | cell-based format | Scientific Literature |