# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA970763 | Binding | Inhibition of Chk1 | 1 | ALA1155876 | single protein format | Scientific Literature | ||
2. | ALA970764 | Binding | Inhibition of human MAPKAP-K2 kinase assessed as residual enzyme activity at 0.1 uM | Homo sapiens | 1 | ALA1155876 | single protein format | Scientific Literature | |
3. | ALA970765 | Binding | Inhibition of Aurora A | 14 | ALA1155876 | single protein format | Scientific Literature | ||
4. | ALA970766 | Binding | Inhibition of Aurora B | 10 | ALA1155876 | single protein format | Scientific Literature | ||
5. | ALA970769 | Functional | Antiproliferative activity against human HT29 cells | Homo sapiens | 8 | ALA1155876 | cell-based format | Scientific Literature | |
6. | ALA970770 | Functional | Antiproliferative activity against human MCF7 cells | Homo sapiens | 8 | ALA1155876 | cell-based format | Scientific Literature | |
7. | ALA970771 | Functional | Antiproliferative activity against human HCT116 cells | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
8. | ALA970772 | Functional | Cell cycle arrested in human MOLT4 cells assessed as accumulation at G2/M phase after 24 hrs | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
9. | ALA970773 | Binding | Inhibition of Aurora A in human HCT cells assessed as loss of autophosphorylation of Aurora A | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
10. | ALA970774 | Binding | Inhibition of Aurora A assessed as separation of centrosomes in human HCT cells | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
11. | ALA970775 | Binding | Inhibition of Aurora B assessed as loss of phospho histone H3 in human H29 cells | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
12. | ALA970776 | Binding | Inhibition of Aurora B assessed as loss of phospho histone H3 in human HCT cells | Homo sapiens | 2 | ALA1155876 | cell-based format | Scientific Literature | |
13. | ALA970777 | Binding | Inhibition of CDK2/CyclinA | 1 | ALA1155876 | single protein format | Scientific Literature | ||
14. | ALA970778 | Binding | Inhibition of CDK3/CyclinE assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | single protein format | Scientific Literature | ||
15. | ALA970779 | Functional | Antitumor activity in human HCT116 cells xenografted athymic mouse assessed as growth inhibition at 1 mg/kg, po qd | Homo sapiens | 1 | ALA1155876 | organism-based format | Scientific Literature | |
16. | ALA970780 | Binding | Inhibition of CDK5/p25 assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | assay format | Scientific Literature | ||
17. | ALA970781 | Binding | Inhibition of CDK6/CyclinD3 assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | protein complex format | Scientific Literature | ||
18. | ALA970782 | Binding | Inhibition of CDK7/CyclinH/MAT1 at assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | single protein format | Scientific Literature | ||
19. | ALA970783 | Binding | Inhibition of CDK9/CyclinT1 assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | assay format | Scientific Literature | ||
20. | ALA970784 | Binding | Inhibition of NEK2 at assessed as residual enzyme activity at 1 uM | 1 | ALA1155876 | single protein format | Scientific Literature |