| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA988266 | B | Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect on foam cell formation | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA988269 | B | Inhibition of normocholesterolemic rabbit liver ACAT | Oryctolagus cuniculus | 8 | assay format | Scientific Literature | ||
| 3. | ALA988270 | F | Antiperoxidative activity in Sprague-Dawley rat brain assessed as inhibition of malonaldehyde level | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 4. | ALA988271 | A | AUC in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA1054936 | P | Octanol-water partition coefficient, log D at pH 7.0 by HPLC method | 24 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA1054937 | B | Inhibition of ACAT in Japanese White rabbit liver microsomes | Oryctolagus cuniculus | 39 | microsome format | Scientific Literature | ||
| 7. | ALA1054938 | F | Anti-foam cell formation activity in human THP1 cells assessed as inhibition of esterified cholesterol accumulation after 24 hrs in presence of Japanese white rabbit high-cholesterol serum | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 8. | ALA5243673 | F | Inhibition of formation of foam cells in rat peritoneal macrophages | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA5243686 | B | Inhibition of SOAT (unknown origin) in macrophage | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA5243687 | B | Inhibition of normocholesterolemic rabbit liver ACAT | Oryctolagus cuniculus | 2 | tissue-based format | Scientific Literature | ||
| 11. | ALA5243688 | F | Antioxidant activity in rat brain homogenate assessed as inhibition of lipid peroxidation | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA5243689 | F | Antioxidant activity in rat brain homogenate assessed as inhibition of lipid peroxidation at 10 uM relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5243690 | A | Plasma concentration in dog at 10 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!