# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA989742 | B | Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coli | Mycobacterium tuberculosis | 29 | ALA1144214 | assay format | Scientific Literature | |
2. | ALA989744 | F | Antituberculosis activity against Mycobacterium tuberculosis | Mycobacterium tuberculosis | 4 | ALA1144214 | organism-based format | Scientific Literature | |
3. | ALA989745 | A | Cytotoxicity against african green monkey Vero cells | Chlorocebus sabaeus | 4 | ALA1144214 | cell-based format | Scientific Literature | |
4. | ALA3720973 | B | Inhibition of purified full-length human PASK expressed in insect cells using MBP protein substrate incubated for 10 mins before ATP addition and measured after 1 hr by kinase-Glo luminescent kinase assay | Homo sapiens | 50 | ALA3714729 | cell-based format | Patent Bioactivity Data | |
5. | ALA3720974 | B | Inhibition of purified human PASK kinase domain expressed in insect cells using MBP protein substrate incubated for 10 mins before ATP addition and measured after 1 hr by kinase-Glo luminescent kinase assay | Homo sapiens | 48 | ALA3714729 | cell-based format | Patent Bioactivity Data | |
6. | ALA4483863 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
7. | ALA4483864 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data |