# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1005407 | B | Inhibition of Eimeria tenella cGMP-dependent protein kinase | Eimeria tenella | 37 | ALA1141668 | single protein format | Scientific Literature | |
2. | ALA1005409 | F | Anticoccidial activity against Eimeria tenella in chickens assessed as reduction of oocysts at 25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria tenella | 23 | ALA1141668 | organism-based format | Scientific Literature | |
3. | ALA1005410 | F | Anticoccidial activity against Eimeria tenella in chickens assessed as reduction of oocysts at 6.25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria tenella | 16 | ALA1141668 | organism-based format | Scientific Literature | |
4. | ALA1005411 | F | Anticoccidial activity against Eimeria tenella in chickens assessed as reduction of oocysts at 12.5 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria tenella | 26 | ALA1141668 | organism-based format | Scientific Literature | |
5. | ALA1005423 | F | Anticoccidial activity against Eimeria acervulina in chickens assessed as reduction of oocysts at 25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria acervulina | 23 | ALA1141668 | organism-based format | Scientific Literature | |
6. | ALA1005424 | F | Anticoccidial activity against Eimeria acervulina in chickens assessed as reduction of oocysts at 6.25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria acervulina | 16 | ALA1141668 | organism-based format | Scientific Literature | |
7. | ALA1007989 | F | Anticoccidial activity against Eimeria acervulina in chickens assessed as reduction of oocysts at 12.5 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria acervulina | 26 | ALA1141668 | organism-based format | Scientific Literature | |
8. | ALA1008000 | F | Anticoccidial activity against Eimeria mitis in chickens assessed as reduction of oocysts at 25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria mitis | 23 | ALA1141668 | organism-based format | Scientific Literature | |
9. | ALA1008001 | F | Anticoccidial activity against Eimeria mitis in chickens assessed as reduction of oocysts at 6.25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria mitis | 16 | ALA1141668 | organism-based format | Scientific Literature | |
10. | ALA1008002 | F | Anticoccidial activity against Eimeria mitis in chickens assessed as reduction of oocysts at 12.5 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria mitis | 26 | ALA1141668 | organism-based format | Scientific Literature | |
11. | ALA1008857 | F | Anticoccidial activity against Eimeria maxima in chickens assessed as reduction of oocysts at 25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria maxima | 23 | ALA1141668 | organism-based format | Scientific Literature | |
12. | ALA1008858 | F | Anticoccidial activity against Eimeria maxima in chickens assessed as reduction of oocysts at 6.25 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria maxima | 16 | ALA1141668 | organism-based format | Scientific Literature | |
13. | ALA1008859 | F | Anticoccidial activity against Eimeria maxima in chickens assessed as reduction of oocysts at 12.5 ppm measured after 8 days by ExMAC assay relative to untreated control | Eimeria maxima | 21 | ALA1141668 | organism-based format | Scientific Literature | |
14. | ALA4400262 | B | Inhibition of Plasmodium falciparum PKG expressed in Escherichia coli Rosetta 2 (DE3) pLysS preincubated for 30 mins using FAM-labeled PKAtide as substrate followed by addition of ATP at Km concentration and measured after 30 mins by microfluidic mobility shift assay | Plasmodium falciparum | 18 | ALA4396957 | assay format | Scientific Literature | |
15. | ALA4400263 | F | Antimalarial activity against blood stage Plasmodium falciparum 3D7A preincubated for 48 hrs followed by [3H]-Hypoxanthine addition and measured after 24 hrs by microbeta scintillation counting method | Plasmodium falciparum | 15 | ALA4396957 | organism-based format | Scientific Literature | |
16. | ALA4400264 | P | Octanol/phosphate buffer solution distribution coefficient, log D of the compound at 100 uM incubated for 12 hrs by LC-MS/MS based shake flask method | 15 | ALA4396957 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA4400265 | A | Stability of the compound in mouse liver microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by NADPH addition and measured after 30 mins by LC-MS/MS analysis relative to control | Mus musculus | 6 | ALA4396957 | microsome format | Scientific Literature |