# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1012851 | F | Antimalarial activity after 72 hrs against chloroquine-sensitive Plasmodium falciparum D10 infected human A+ erythrocytes in Makler LDH reporter assay | Plasmodium falciparum | 18 | ALA1139381 | organism-based format | Scientific Literature | |
2. | ALA1012852 | F | Antimalarial activity after 72 hrs against chloroquine-resistant Plasmodium falciparum W2 infected human A+ erythrocytes by Makler LDH reporter assay | Plasmodium falciparum | 18 | ALA1139381 | organism-based format | Scientific Literature | |
3. | ALA1012853 | F | Antimalarial activity after 24 hrs against chloroquine-sensitive Plasmodium falciparum 3D7 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 9 | ALA1139381 | organism-based format | Scientific Literature | |
4. | ALA1012854 | F | Antimalarial activity after 24 hrs against chloroquine-resistant synchronous Plasmodium falciparum K1 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 10 | ALA1139381 | organism-based format | Scientific Literature | |
5. | ALA1012855 | F | Antimalarial activity after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 13 | ALA1139381 | organism-based format | Scientific Literature | |
6. | ALA1012856 | F | Antimalarial activity after 48 hrs against chloroquine-resistant asynchronous Plasmodium falciparum K1 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 13 | ALA1139381 | organism-based format | Scientific Literature | |
7. | ALA1012857 | A | Cytotoxicity against mouse NSO cells by MTT assay | Mus musculus | 10 | ALA1139381 | cell-based format | Scientific Literature | |
8. | ALA1012858 | A | Cytotoxicity against human Daudi cells by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
9. | ALA1012859 | A | Cytotoxicity against PHA-stimulated human lymphocytes by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
10. | ALA1012860 | A | Cytotoxicity against human KB cells by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
11. | ALA1012861 | F | Antimalarial activity as reduced parasitaemia against Plasmodium chabaudi AS infected CD1 mice (Mus musculus) at 50 mg/kg/day peroral dose | Plasmodium chabaudi | 7 | ALA1139381 | organism-based format | Scientific Literature | |
12. | ALA1015406 | F | Antimalarial activity as reduced parasitaemia against Plasmodium berghei ANKA infected CD1 mice (Mus musculus) on daily peroral dose over 4 days | Plasmodium berghei | 4 | ALA1139381 | organism-based format | Scientific Literature | |
13. | ALA1015413 | A | Apparent volume of distribution in CD-COBS rat at 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139381 | organism-based format | Scientific Literature | |
14. | ALA1015414 | A | Elimination half life in CD-COBS rat at 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139381 | organism-based format | Scientific Literature | |
15. | ALA2176141 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 infected in human RBC after 72 hrs by parasite lactate dehydrogenase assay | Plasmodium falciparum | 27 | ALA2169878 | organism-based format | Scientific Literature | |
16. | ALA2176142 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 infected in human RBC after 72 hrs by parasite lactate dehydrogenase assay | Plasmodium falciparum | 27 | ALA2169878 | organism-based format | Scientific Literature | |
17. | ALA2176143 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 infected in human erythrocytes assessed as inhibition of [3H]hypoxanthine incorporation incubated for 48 hrs prior to [3H]hypoxanthine addition measured after 48 hrs by liquid scintillation counting | Plasmodium falciparum | 27 | ALA2169878 | organism-based format | Scientific Literature | |
18. | ALA2176144 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 infected in human erythrocytes assessed as inhibition of [3H]hypoxanthine incorporation incubated for 48 hrs prior to [3H]hypoxanthine addition measured after 48 hrs by liquid scintillation counting | Plasmodium falciparum | 27 | ALA2169878 | organism-based format | Scientific Literature | |
19. | ALA2176145 | F | Resistance ratio of IC50 for chloroquine-resistant Plasmodium falciparum W2 to IC50 for chloroquine-sensitive Plasmodium falciparum D10 | Plasmodium falciparum | 10 | ALA2169878 | organism-based format | Scientific Literature | |
20. | ALA2176146 | F | Resistance ratio of IC50 for chloroquine-resistant Plasmodium falciparum K1 to IC50 for chloroquine-sensitive Plasmodium falciparum NF54 | Plasmodium falciparum | 8 | ALA2169878 | organism-based format | Scientific Literature |