# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1012851 | F | Antimalarial activity after 72 hrs against chloroquine-sensitive Plasmodium falciparum D10 infected human A+ erythrocytes in Makler LDH reporter assay | Plasmodium falciparum | 18 | ALA1139381 | organism-based format | Scientific Literature | |
2. | ALA1012852 | F | Antimalarial activity after 72 hrs against chloroquine-resistant Plasmodium falciparum W2 infected human A+ erythrocytes by Makler LDH reporter assay | Plasmodium falciparum | 18 | ALA1139381 | organism-based format | Scientific Literature | |
3. | ALA1012853 | F | Antimalarial activity after 24 hrs against chloroquine-sensitive Plasmodium falciparum 3D7 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 9 | ALA1139381 | organism-based format | Scientific Literature | |
4. | ALA1012854 | F | Antimalarial activity after 24 hrs against chloroquine-resistant synchronous Plasmodium falciparum K1 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 10 | ALA1139381 | organism-based format | Scientific Literature | |
5. | ALA1012855 | F | Antimalarial activity after 48 hrs against chloroquine-sensitive Plasmodium falciparum NF54 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 13 | ALA1139381 | organism-based format | Scientific Literature | |
6. | ALA1012856 | F | Antimalarial activity after 48 hrs against chloroquine-resistant asynchronous Plasmodium falciparum K1 infected human A+ erythrocytes by [3H]hypoxanthine uptake | Plasmodium falciparum | 13 | ALA1139381 | organism-based format | Scientific Literature | |
7. | ALA1012857 | A | Cytotoxicity against mouse NSO cells by MTT assay | Mus musculus | 10 | ALA1139381 | cell-based format | Scientific Literature | |
8. | ALA1012858 | A | Cytotoxicity against human Daudi cells by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
9. | ALA1012859 | A | Cytotoxicity against PHA-stimulated human lymphocytes by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
10. | ALA1012860 | A | Cytotoxicity against human KB cells by MTT assay | Homo sapiens | 10 | ALA1139381 | cell-based format | Scientific Literature | |
11. | ALA1012861 | F | Antimalarial activity as reduced parasitaemia against Plasmodium chabaudi AS infected CD1 mice (Mus musculus) at 50 mg/kg/day peroral dose | Plasmodium chabaudi | 7 | ALA1139381 | organism-based format | Scientific Literature | |
12. | ALA1015405 | F | Antimalarial activity as reduced parasitaemia against Plasmodium berghei ANKA infected CD1 mice (Mus musculus) at 50 mg/kg/day peroral dose over 4 days | Plasmodium berghei | 1 | ALA1139381 | organism-based format | Scientific Literature | |
13. | ALA1015410 | F | Antimalarial activity as increased survival against Plasmodium berghei ANKA infected CD1 mice (Mus musculus) at 50 mg/kg/day peroral dose over 4 days | Plasmodium berghei | 1 | ALA1139381 | organism-based format | Scientific Literature | |
14. | ALA1015412 | F | Inhibition of beta-hematin assessed as molar equivalents at pH 2.7 after 18 hrs by spectrophotometric microassay relative to hemin | 4 | ALA1139381 | assay format | Scientific Literature | ||
15. | ALA1015413 | A | Apparent volume of distribution in CD-COBS rat at 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139381 | organism-based format | Scientific Literature | |
16. | ALA1015414 | A | Elimination half life in CD-COBS rat at 5 mg/kg, iv | Rattus norvegicus | 2 | ALA1139381 | organism-based format | Scientific Literature | |
17. | ALA1015415 | A | Ratio of drug level in blood to plasma of CD-COBS rat at 5 mg/kg, iv | Rattus norvegicus | 1 | ALA1139381 | organism-based format | Scientific Literature | |
18. | ALA1015416 | A | AUC (0 to t) in CD-COBS rat at 50 mg/kg, po after 60 mins | Rattus norvegicus | 1 | ALA1139381 | organism-based format | Scientific Literature | |
19. | ALA1015417 | A | Cmax in CD-COBS rat at 50 mg/kg, po after 60 mins | Rattus norvegicus | 1 | ALA1139381 | organism-based format | Scientific Literature | |
20. | ALA1015418 | A | AUC (0 to t) in CD1 albino mouse at 50 mg/kg, po after 60 mins | Mus musculus | 1 | ALA1139381 | organism-based format | Scientific Literature |