# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1011781 | B | Binding affinity to human purified SARP2 by fluorescent polarization assay | Homo sapiens | 31 | single protein format | Scientific Literature | ||
2. | ALA1011782 | P | Aqueous solubility of the compound | 31 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA1012645 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
4. | ALA1012646 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as 2 fold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
5. | ALA1012647 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as 4 fold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
6. | ALA1072833 | B | Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
7. | ALA1072834 | P | Aqueous solubility of the compound | 40 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA1072835 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
9. | ALA1072836 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for twofold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
10. | ALA1072837 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for fourfold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
11. | ALA1072838 | P | Aqueous solubility at pH 7.4 | 18 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA1072839 | A | Half life in human liver microsomes at 1 uM | Homo sapiens | 17 | microsome format | Scientific Literature | ||
13. | ALA1072840 | A | Half life in rat liver microsomes at 1 uM | Rattus norvegicus | 18 | microsome format | Scientific Literature |