# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1011781 | B | Binding affinity to human purified SARP2 by fluorescent polarization assay | Homo sapiens | 31 | single protein format | Scientific Literature | ||
2. | ALA1011782 | P | Aqueous solubility of the compound | 31 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA1012645 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
4. | ALA1012646 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as 2 fold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
5. | ALA1012647 | F | Antagonist activity at human WNT3 expressed in human U2OS cells assessed as 4 fold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
6. | ALA1012650 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
7. | ALA1012651 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 4 | microsome format | Scientific Literature | ||
8. | ALA1012652 | A | Inhibition of CYP3A4 at 3 uM | 5 | single protein format | Scientific Literature | |||
9. | ALA1012653 | A | Inhibition of CYP2D6 at 3 uM | 5 | single protein format | Scientific Literature | |||
10. | ALA1012654 | A | Inhibition of CYP2C9 at 3 uM | 5 | single protein format | Scientific Literature | |||
11. | ALA1012655 | F | Induction of bone formation in mouse calvaria assessed as increase in total bone area at 1 nM after 7 days relative to control | Mus musculus | 1 | tissue-based format | Scientific Literature |