# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3562002 | Functional | PubChem BioAssay. Immunotoxin (HA22) sensitization/mitigation study. Vehicle arm (PBS). (Class of assay: confirmatory) | 370 | ALA1201862 | assay format | PubChem BioAssays | ||
2. | ALA3562018 | Functional | PubChem BioAssay. Immunotoxin (SS1P) sensitization/mitigation study - treatment arm. (Class of assay: confirmatory) | 401 | ALA1201862 | assay format | PubChem BioAssays | ||
3. | ALA3562034 | Functional | PubChem BioAssay. Immunotoxin (SS1P) sensitization/mitigation study. Vehicle arm (DMEM). (Class of assay: confirmatory) | 344 | ALA1201862 | assay format | PubChem BioAssays | ||
4. | ALA3562067 | Functional | PubChem BioAssay. Immunotoxin (HA22) sensitization/mitigation study - treatment arm (low dose). (Class of assay: confirmatory) | 407 | ALA1201862 | organism-based format | PubChem BioAssays | ||
5. | ALA3756564 | Binding | Binding affinity to TNIK (unknown origin) | Homo sapiens | 3 | ALA3751797 | single protein format | Scientific Literature | |
6. | ALA3756567 | Binding | Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 3 uM ATP | Homo sapiens | 2 | ALA3751797 | single protein format | Scientific Literature | |
7. | ALA3756748 | Binding | Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 30 uM ATP | Homo sapiens | 2 | ALA3751797 | single protein format | Scientific Literature | |
8. | ALA3756749 | Binding | Competitive inhibition of recombinant TNIK (unknown origin) using LRRKtide as substrate after 1 hr in presence of 300 uM ATP | Homo sapiens | 2 | ALA3751797 | single protein format | Scientific Literature | |
9. | ALA3756765 | Binding | Inhibition of TNIK in human NCI-H1703 cells transfected with lentiviral vector 7TFP assessed as reduction of GSK3 inhibitor X activated TNIK-mediated Wnt/TCF/beta-catenin-dependent transcription at 10 uM after 24 hrs by luciferase reporter assay | Homo sapiens | 4 | ALA3751797 | cell-based format | Scientific Literature | |
10. | ALA3756766 | ADME | Cytotoxicity against human NCI-H1703 cells transfected with lentiviral vector 7TFP assessed as cell viability at 10 uM after 72 hrs by ATPlite assay | Homo sapiens | 4 | ALA3751797 | cell-based format | Scientific Literature | |
11. | ALA3756767 | Functional | Cytotoxicity against Wnt/beta-catenin signalling dependent human HCT116 cells assessed as cell viability at 10 uM after 72 hrs by ATPlite assay | Homo sapiens | 4 | ALA3751797 | cell-based format | Scientific Literature | |
12. | ALA3756768 | Functional | Cytotoxicity against Wnt/beta-catenin signalling dependent human LoVo cells assessed as cell viability at 10 uM after 72 hrs by ATPlite assay | Homo sapiens | 4 | ALA3751797 | cell-based format | Scientific Literature | |
13. | ALA1787525 | Binding | Binding affinity to human KIT incubated for 1 hr by kinase binding assay | Homo sapiens | 39 | ALA1782045 | single protein format | Scientific Literature | |
14. | ALA1787527 | Binding | Binding affinity to human KIT D816V mutant incubated for 1 hr by kinase binding assay | Homo sapiens | 39 | ALA1782045 | single protein format | Scientific Literature | |
15. | ALA1908399 | Binding | Binding constant for BRSK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
16. | ALA1908400 | Binding | Binding constant for MAPKAPK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
17. | ALA1908401 | Binding | Binding constant for NEK9 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
18. | ALA1908402 | Binding | Binding constant for MYLK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
19. | ALA1908403 | Binding | Binding constant for MLK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
20. | ALA1908404 | Binding | Binding constant for DCAMKL3 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature |