# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA961646 | Physicochemical | Hydrolytic stability assessed as compound degradation at 2 mg in sodium dihydrogen phosphate buffered 0.3% sodium carboxymethylcellulose solution at pH 7.4 after 45 hrs by HPLC | 56 | ALA1153929 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA961669 | Functional | Cytotoxicity against human CNE cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA1153929 | cell-based format | Scientific Literature | |
3. | ALA961671 | Functional | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay | Homo sapiens | 31 | ALA1153929 | cell-based format | Scientific Literature | |
4. | ALA961673 | Functional | Cytotoxicity against human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA1153929 | cell-based format | Scientific Literature | |
5. | ALA2405592 | Binding | Inhibition of 11beta-HSD2 in human kidney microsomes using [3H]-cortisol as substrate assessed as formation of cortisone at 100 uM after 30 mins by radiometric analysis relative to control | Homo sapiens | 36 | ALA2401685 | microsome format | Scientific Literature | |
6. | ALA2405593 | Binding | Inhibition of 11beta-HSD2 in rat kidney microsomes using [3H]-CORT as substrate assessed as formation of 11-DHC at 100 uM after 30 mins by radiometric analysis relative to control | Rattus norvegicus | 36 | ALA2401685 | microsome format | Scientific Literature | |
7. | ALA2405594 | Binding | Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol after 60 to 90 mins by radiometric analysis | Homo sapiens | 10 | ALA2401685 | microsome format | Scientific Literature | |
8. | ALA2405595 | Binding | Inhibition of human 11beta-HSD1 transfected in CHOP cells | Homo sapiens | 11 | ALA2401685 | cell-based format | Scientific Literature | |
9. | ALA2405596 | Binding | Ratio of curcumin IC50 to compound IC50 for human 11beta-HSD1 transfected in CHOP cells | Homo sapiens | 10 | ALA2401685 | cell-based format | Scientific Literature | |
10. | ALA2405598 | Binding | Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uM | Rattus norvegicus | 15 | ALA2401685 | assay format | Scientific Literature | |
11. | ALA2405605 | Binding | Inhibition of 11beta-HSD1 in rat testis microsomes using [3H]-11-DHC as substrate assessed as formation of CORT after 60 to 90 mins by radiometric analysis | Rattus norvegicus | 9 | ALA2401685 | microsome format | Scientific Literature | |
12. | ALA5147807 | Functional | Antibacterial activity against Enterobacter cloacae 45301 assessed as inhibition zone incubated for 24 hrs by agar plate method | Enterobacter cloacae | 2 | ALA5143672 | organism-based format | Scientific Literature |