| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA962456 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 0.3 uM after 18 hrs | Homo sapiens | 26 | ALA1153852 | cell-based format | Scientific Literature | |
| 2. | ALA962457 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 3 uM after 18 hrs | Homo sapiens | 26 | ALA1153852 | cell-based format | Scientific Literature | |
| 3. | ALA962458 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone after 18 hrs | Homo sapiens | 12 | ALA1153852 | cell-based format | Scientific Literature | |
| 4. | ALA962462 | B | Inhibition of human 17beta-HSD1 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-E1 in to [14C]-E2 at 1 uM | Homo sapiens | 3 | ALA1153852 | cell-based format | Scientific Literature | |
| 5. | ALA962463 | B | Inhibition of human 17beta-HSD3 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 0.1 uM | Homo sapiens | 4 | ALA1153852 | cell-based format | Scientific Literature | |
| 6. | ALA962464 | B | Inhibition of human 17beta-HSD3 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 1 uM | Homo sapiens | 4 | ALA1153852 | cell-based format | Scientific Literature | |
| 7. | ALA963254 | F | Estrogenic activity in human ZR-75-1 cells expressing estrogen receptor assessed as estrogen-induced cell proliferation at 1 uM after 9 days relative to estrogen | Homo sapiens | 3 | ALA1153852 | cell-based format | Scientific Literature | |
| 8. | ALA963255 | F | Antiestrogenic activity in human ZR-75-1 cells expressing estrogen receptor assessed as inhibition of estrogen-induced cell proliferation at 0.03 uM after 9 days relative to estrogen | Homo sapiens | 2 | ALA1153852 | cell-based format | Scientific Literature | |
| 9. | ALA963256 | F | Antiestrogenic activity in human ZR-75-1 cells expressing estrogen receptor assessed as inhibition of estrogen-induced cell proliferation at 1 uM after 9 days relative to estrogen | Homo sapiens | 2 | ALA1153852 | cell-based format | Scientific Literature | |
| 10. | ALA963258 | F | Androgenic activity in mouse SC115 cells expressing androgen receptor assessed as DHT-induced cell proliferation at 0.1 uM after 10 days relative to DHT | Mus musculus | 3 | ALA1153852 | cell-based format | Scientific Literature | |
| 11. | ALA963259 | F | Androgenic activity in mouse SC115 cells expressing androgen receptor assessed as DHT-induced cell proliferation at 1 uM after 10 days relative to DHT | Mus musculus | 3 | ALA1153852 | cell-based format | Scientific Literature | |
| 12. | ALA963263 | B | Binding affinity to rat uterus estrogen receptor at 0.01 uM | Rattus norvegicus | 4 | ALA1153852 | single protein format | Scientific Literature | |
| 13. | ALA963264 | B | Binding affinity to rat uterus estrogen receptor at 1 uM | Rattus norvegicus | 1 | ALA1153852 | single protein format | Scientific Literature | |
| 14. | ALA963267 | B | Binding affinity to rat ventral prostate androgen receptor at 0.01 uM | Rattus norvegicus | 4 | ALA1153852 | tissue-based format | Scientific Literature | |
| 15. | ALA963268 | B | Binding affinity to rat ventral prostate androgen receptor at 1 uM | Rattus norvegicus | 1 | ALA1153852 | tissue-based format | Scientific Literature | |
| 16. | ALA965787 | B | Binding affinity to rat uterus progesterone receptor at 0.01 uM | Rattus norvegicus | 4 | ALA1153852 | single protein format | Scientific Literature | |
| 17. | ALA965788 | B | Binding affinity to rat uterus progesterone receptor at 1 uM | Rattus norvegicus | 1 | ALA1153852 | single protein format | Scientific Literature | |
| 18. | ALA965791 | B | Binding affinity to rat liver glucocorticoid receptor at 0.01 uM | Rattus norvegicus | 4 | ALA1153852 | assay format | Scientific Literature | |
| 19. | ALA965792 | B | Binding affinity to rat liver glucocorticoid receptor at 1 uM | Rattus norvegicus | 1 | ALA1153852 | assay format | Scientific Literature | |
| 20. | ALA1106725 | B | Inhibition of human 17beta-HSD7 expressed in HEK293 cells assessed as inhibition of reduction of [14C]estrone into [14C]estradiol at 3 uM after 7 hrs | Homo sapiens | 124 | ALA1154295 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!