| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA960166 | F | Antiviral activity against SIV in human CEM cells assessed as inhibition of virus-induced cytopathogenicity | Simian immunodeficiency virus | 31 | organism-based format | Scientific Literature | ||
| 2. | ALA960167 | A | Cytotoxicity against human CEM cells | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 3. | ALA960168 | A | Therapeutic index, TC50 for human CEM cells to EC50 for SIV | 30 | cell-based format | Scientific Literature | |||
| 4. | ALA960170 | B | Binding affinity to HIV1 capsid assessed as assembly rate per minute by ultraviolet spectrophotometry assay | Human immunodeficiency virus 1 | 30 | assay format | Scientific Literature | ||
| 5. | ALA960174 | B | Binding affinity to human cyclophilin A by intrinsic tryptophan fluorescence titration assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 6. | ALA960175 | B | Inhibition of human cyclophilin A at 6 degC | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 7. | ALA3060856 | B | Inhibition of Homo sapiens (human) cyclophilin A PPIase activity expressed in Escherichia coli BL21(DE3) using Suc-AAPF-pNA as substrate measured after 6 secs for 20 secs by spectrophotometric analysis | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 8. | ALA3060857 | B | Binding affinity to Homo sapiens (human) cyclophilin A expressed in Escherichia coli BL21(DE3) by fluorescence titration assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 9. | ALA3060858 | T | Toxicity index, ratio of TC50 for human CEM174 cells to EC50 for Simian immunodeficiency virus | 20 | cell-based format | Scientific Literature | |||
| 10. | ALA3060859 | A | Cytotoxicity against Homo sapiens (human) CEM174 by MTT assay | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 11. | ALA3060860 | F | Antiviral activity against Simian immunodeficiency virus infected CEM174 cells assessed as inhibition of virus-induced syncytium after 5 days by microscopic analysis | Simian immunodeficiency virus | 20 | organism-based format | Scientific Literature | ||
| 12. | ALA3060861 | B | Inhibition of Human immunodeficiency virus 1 capsid protein expressed in Escherichia coli BL21(DE3) assessed as capsid assembly rate measured every 5 secs by spectrofluorometric analysis (Rvb = 51.88 x 10'-5 OD/s) | Human immunodeficiency virus 1 | 14 | assay format | Scientific Literature |
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